Publications by authors named "Leandro Gentile"

Objectives: to evaluate the disparities in access to cancer screening programmes in the Province of Pavia (Lombardy Region, Northern Italy), along with identifying the factors influencing these disparities; to assess the impact of the pandemic emergency on invitation and screening coverage in the three organized screening programmes, which are provided free of charge to the target population.

Design: observational retrospective study covering both the pre-pandemic and the pandemic periods.

Setting And Participants: for breast cancer screening, the eligible population comprises women aged 45 to 74; colorectal cancer screening is offered to men and women aged 50 to 74; cervical cancer screening is tailored based on women age.

View Article and Find Full Text PDF
Article Synopsis
  • - This study analyzes the Lombardia Cardiac Arrest Registry in Italy, focusing on post-out-of-hospital cardiac arrest (OHCA) intra-hospital mortality and the impact of patient characteristics and emergency health services (EMS) management on patient outcomes.
  • - Out of over 12,000 OHCA patients studied from 2015 to 2022, a significant number (61.6%) died in the hospital, with factors like non-shockable presenting rhythm and longer CPR times being associated with higher mortality risks.
  • - The findings reveal that the risk of death in the hospital increases with a non-shockable rhythm (27% higher) and longer EMS response times, and that patients' outcomes are primarily influenced by their initial
View Article and Find Full Text PDF
Article Synopsis
  • The COVID-19 pandemic significantly accelerated research and development in vaccines, increasing resources and innovation while revising regulatory processes to boost production and distribution capacities.
  • This narrative review outlines the effects of COVID-19 on vaccine research, presenting a comparison of various vaccine technologies and highlighting their pros and cons.
  • With nearly 1,000 vaccine candidates current as of 2023, the review emphasizes future challenges and opportunities in immunization strategies, as public funding has largely backed COVID-19 vaccine development but is expected to decrease post-pandemic.
View Article and Find Full Text PDF

There is no single model for Population Health Management (PHM) and different definitions have been proposed. All PHM models and definitions share the overall aim of improving population health and reduce healthcare costs. To achieve these objectives, PHM makes use of conceptual tools such as the Chronic Care Model and predictive medicine, and technical tools such as information systems and computational and record-linkage techniques to collect and analyse data.

View Article and Find Full Text PDF

Unlabelled: Background and aim: Social media platforms are common sources of information, even more so during the COVID-19 pandemic. YouTube is the second most popular social media platform both in Italy and globally. Following criticisms regarding quality control during the pandemic, banners that would direct viewers to official health information sources were incorporated into Youtube videos related to COVID-19.

View Article and Find Full Text PDF

Background And Aim: Enhancing public health communication during a global crisis is crucial to promote resilience. This study examines the influence of health communication in ten countries, analysing its positive and negative impact on society's behavior regarding the origin, symptoms, and prevention of SARS-CoV-2.

Methods: A comprehensive narrative analysis of available data was conducted to evaluate societal and resilience responses during the COVID-19 pandemic.

View Article and Find Full Text PDF

Detecting SARS-CoV-2 remains a critical component in the global effort to control COVID-19, particularly with the emergence of variants. Since the outbreak, diagnostic techniques have evolved to meet different contexts and needs. Methods: In this study, we analyzed the use of these techniques in five countries (i.

View Article and Find Full Text PDF

Excess mortality estimates are considered relevant indicators of direct and indirect pandemic effects on the population. Scant data have been published on cause-specific excess mortality. Using individual-level administrative data covering the Pavia province of Italian northern Lombardy region, we provided all-cause and cause-specific raw (RMR) and age-standardized (ASMR) mortality rates in 2021 and 2015-2019, the rate ratio, and 95% confidence intervals, overall and by sex.

View Article and Find Full Text PDF

Worldwide, the COVID-19 pandemic disrupted healthcare services, including cervical cancer management, and an increased burden for this condition is expected. This systematic review synthetizes the available evidence on the impact of the pandemic on prevention, diagnosis and treatment of cervical cancer. Searches were performed on PubMed, Embase, and Scopus for relevant studies on these topics with the purpose of comparing service access and care delivery before and during COVID-19 pandemic.

View Article and Find Full Text PDF

Aims: Using the principles of clinical governance, a patient-centred approach intended to promote holistic quality improvement, we designed a prospective, multicentre study in patients with acute coronary syndrome (ACS). We aimed to verify and quantify consecutive inclusion and describe relative and absolute effects of indicators of quality for diagnosis and therapy.

Methods And Results: Administrative codes for invasive coronary angiography and acute myocardial infarction were used to estimate the ACS universe.

View Article and Find Full Text PDF

Background and aim Contact tracing is a key element of epidemiologic investigation and active surveillance during infectious diseases outbreaks. Digital contact tracing (DCT) are new technologies that have been increasingly adopted in different countries to support conventional contact tracing efforts to control the COVID-19 pandemic. However, scant evidence is available on its public health effectiveness.

View Article and Find Full Text PDF

Aim: To evaluate the University of Pavia students about physical activity (PA) changes before, during and after the COVID-19 pandemic.

Methods: The International Physical Activity Questionnaires (IPAQ) survey was employed to evaluate the PA in three periods: the pre-pandemic period, during national stay-at-home order (March 9th - May 4th 2020), current PA. Exercise intensity for each period was defined using the Metabolic Equivalent of Task (Met) as unit of measurement.

View Article and Find Full Text PDF

Background And Aim Of The Work: During the COVID-19 pandemic, many countries adopted restrictive measures to mitigate infection spread, which might have influenced people's lifestyle and dietary habits. We conducted a systematic review to evaluate the impact of national lockdowns on adherence to the Mediterranean Diet (MD).

Methods: Studies were identified searching Medline, Embase, Web of Science, and the Cochrane Library.

View Article and Find Full Text PDF

Background: Pharmacological treatment of iron deficiency anaemia can reduce red blood cell (RBC) transfusions. Intravenous iron provides a more effective and quicker correction of iron deficiency anaemia than oral iron, and third-generation high-dose intravenous iron formulations allow the complete correction of iron deficiency with just one or two drug infusions, thus facilitating iron supplementation therapy and reducing transfusion requirement.

Material And Methods: In an observational, retrospective study we compared RBC transfusion requirement during hospitalisation and within 3 months of hospital discharge in 88 patients with iron deficiency anaemia treated with high-dose ferric carboxymaltose and in 85 patients treated with ferric gluconate while hospitalised in the Internal Medicine unit of our Institution.

View Article and Find Full Text PDF

Background: Retirement is a life-course transition likely to affect, through different mechanisms, behavioural risk factors' patterns and, ultimately, health outcomes. We assessed the impact of transitioning to retirement on lifestyle habits and perceived health status in a nationwide cohort of Italian adults.

Methods: We analysed data from a large cohort of Italian adults aged 55-70, derived from linking six waves of the Participation, Labour, Unemployment Survey (PLUS), a national survey representative of the Italian workforce population, conducted between 2010 and 2018.

View Article and Find Full Text PDF

The flu vaccination rate is still too low, both among healthcare providers (HCPs) and among health sciences university students. This study aims to assess the reasons of past and future flu vaccination acceptance among health sciences university students, and second, to identify what interventions would be helpful to foster acceptance of the flu vaccination among HCPs. A multicentre cross-sectional study was performed, using a validated questionnaire administered to health sciences students enrolled in 14 Italian universities.

View Article and Find Full Text PDF
Article Synopsis
  • Diabetic patients, especially those with type 1 diabetes mellitus (T1DM), are at a greater risk for infections and serious complications, yet there’s limited research on their influenza vaccination rates.
  • In a study of 251 T1DM patients in Milan, only 36% reported receiving the flu vaccine, which dropped to 21.7% based on official registries—far below the target coverage of 75%.
  • Results showed that most patients trust diabetologists for vaccine information, indicating a need for targeted vaccination campaigns involving diabetes specialists to improve immunization rates.
View Article and Find Full Text PDF

COVID-19 is a novel infectious disease which has rapidly spread around the globe, disrupting several aspects of public life over the past year. After numerous infection clusters emerged among travelers hosted in ski resorts in early 2020, several European countries closed ski areas. These measures were mostly upheld throughout the 2020 and 2021 winter season, generating significant economic loss for mountain communities.

View Article and Find Full Text PDF

The concept of Vaccine Hesitancy has begun to appear in the scientific landscape, referring to the reluctance of a growing proportion of people to accept the vaccination offer. A variety of factors were identified as being associated with vaccine hesitancy but there was no universal algorithm and currently there aren't any established metrics to assess either the presence or impact of vaccine hesitancy. The aim of this study was to systematically review the published questionnaires evaluating parental vaccine hesitancy, to highlight the differences among these surveys and offer a general overview on this matter.

View Article and Find Full Text PDF

Aim: To develop an instrument to investigate knowledge and predictive factors of needlestick and sharps injuries (NSIs) in nursing students during clinical placements.

Design: Instrument development and cross-sectional study for psychometric testing.

Methods: A self-administered instrument including demographic data, injury epidemiology and predictive factors of NSIs was developed between October 2018-January 2019.

View Article and Find Full Text PDF

This paper outlines the characteristics of scientific leadership and the role of Scientific Associations with their specific activities. The recent activities of the Lombard Academy of Public Health are subsequently described, including the creation, in 2019, of the Academy of young leaders in public health. Comparing to other sectors, scientific leadership dynamics take into consideration different aspects.

View Article and Find Full Text PDF

Background: Vaccines are an important tool to prevent communicable diseases. Despite their importance, vaccines seem to be victims of their own success and declining levels of vaccination uptake have been recorded in Europe and Italy. For this reason, Italy introduced a new mandatory vaccination law on July 31, 2017.

View Article and Find Full Text PDF