Publications by authors named "Leah S Fischer"

Article Synopsis
  • Global measles vaccine coverage has been stuck at around 85% for over ten years, and a new microarray patch (MR-MAP) could help increase this by simplifying the vaccination process.
  • Clinical trials show that MR-MAPs are safe and effective for infants, similar to traditional syringe vaccinations.
  • A demand estimation tool was developed using data from 180 WHO countries, predicting varying demand for MR-MAPs based on different vaccination strategies, with estimates ranging from 137 million to 2.587 billion doses needed in different scenarios by 2025-2034.
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Case investigation and contact tracing (CICT) are public health measures that aim to break the chain of pathogen transmission. Changes in viral characteristics of COVID-19 variants have likely affected the effectiveness of CICT programs. We estimated and compared the cases averted in Vermont when the original COVID-19 strain circulated (Nov.

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Background: Facing a surge of COVID-19 cases in late August 2021, the U.S. state of Illinois re-enacted its COVID-19 mask mandate for the general public and issued a requirement for workers in certain professions to be vaccinated against COVID-19 or undergo weekly testing.

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Article Synopsis
  • The Philadelphia Department of Public Health revised its COVID-19 contact tracing methods in summer 2021 due to limited personnel resources.
  • The new protocol focuses on prioritizing recent cases and reduces the time spent on each case from 21-30 hours down to 8-11 hours.
  • Despite the adjustment, the department was able to maintain the effectiveness of the contact tracing program.
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Background: During November 2019-October 2021, a pediatric influenza vaccination demonstration project was conducted in four sub-counties in Kenya. The demonstration piloted two different delivery strategies: year-round vaccination and a four-month vaccination campaign. Our objective was to compare the costs of both delivery strategies.

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Introduction: During the COVID-19 pandemic, the U.S. Centers for Disease Control and Prevention developed a simple spreadsheet-based tool to help state and local public health officials assess the performance and impact of COVID-19 case investigation and contact tracing in their jurisdiction.

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Importance: Some US states have issued COVID-19 vaccine mandates; however, the association of these mandates with vaccination rates remains unknown.

Objective: To examine the association between announcing state-issued COVID-19 vaccine mandates that did not provide a test-out option for workers and the vaccine administration rates in terms of state-level first-dose vaccine administration and series completion coverage.

Design, Setting, And Participants: This cross-sectional study used publicly available, state-level aggregated panel data to fit linear regression models with 2-way fixed effects (state and time) estimating vaccine coverage changes 8 weeks before and 8 weeks after a state-issued COVID-19 vaccine mandate was announced.

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Importance: Evidence of the impact of COVID-19 case investigation and contact tracing (CICT) programs is lacking, but policy makers need this evidence to assess the value of such programs.

Objective: To estimate COVID-19 cases and hospitalizations averted nationwide by US states' CICT programs.

Design, Setting, And Participants: This decision analytical model study used combined data from US CICT programs (eg, proportion of cases interviewed, contacts notified or monitored, and days to case and contact notification) with incidence data to model outcomes of CICT over a 60-day period (November 25, 2020, to January 23, 2021).

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Article Synopsis
  • - Outbreaks of emerging infectious diseases like H1N1, Ebola, and Zika pose ongoing health threats and are often accompanied by stigma that hinders people from adopting healthy behaviors.
  • - Stigma can lead to more severe health issues, ongoing transmission, and challenges in managing outbreaks, with lessons learned from nearly 40 years of HIV/AIDS research being particularly relevant.
  • - The paper suggests strategies to reduce stigma during outbreaks, emphasizing that simple, practical approaches can enhance public health responses and control measures against diseases like Ebola and Zika.
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Background: In the context of the opioid epidemic, injection drug use (IDU)-related infections are an escalating health issue for infectious diseases (ID) physicians in the United States.

Methods: We conducted a mixed methods survey of the Infectious Diseases Society of America's Emerging Infections Network between February and April 2017 to evaluate perspectives relating to care of persons who inject drugs (PWID). Topics included the frequency of and management strategies for IDU-related infection, the availability of addiction services, and the evolving role of ID physicians in substance use disorder (SUD) management.

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Article Synopsis
  • Emergency departments (EDs) are crucial for providing rapid care to patients with severe infections and often face challenges in conducting timely research despite their continuous patient flow.
  • The ncy ID NET is a national initiative that showcases how EDs can collect real-time data and engage in research, partnering with organizations like the CDC to study various infectious diseases.
  • The paper reviews key developments in ncy ID NET's history from 1995 to 2017, highlighting the creation of a multisite research network and its collaborative efforts on diverse clinical issues relevant to emergency care.
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The federal budgeting process affects a wide range of people who work in public health, including those who work for government at local, state, and federal levels; those who work with government; those who operate government-funded programs; and those who receive program services. However, many people who are affected by the federal budget are not aware of or do not understand how it is appropriated or executed. This commentary is intended to give non-financial experts an overview of the federal budget process to address public health emergencies.

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Mathematical models incorporate various data sources and advanced computational techniques to portray real-world disease transmission and translate the basic science of infectious diseases into decision-support tools for public health. Unlike standard epidemiologic methods that rely on complete data, modeling is needed when there are gaps in data. By combining diverse data sources, models can fill gaps when critical decisions must be made using incomplete or limited information.

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Purpose: Assess relationships between having a medical home and health care-seeking behavior attitudes among parents of low-income children with non-urgent encounters in acute settings (emergency, urgent care centers).

Methods: We analyzed data from 1,743 publicly insured children within non-urgent encounters. Parents completed surveys assessing medical home access and attitudes regarding health care-seeking behavior.

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Context: CDC's Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Cooperative Agreement aims to help health departments strengthen core epidemiology capacity needed to respond to a variety of emerging infectious diseases. In fiscal year 2014, $6 million was awarded to 41 health departments for flexible epidemiologists (FEs). FEs were intended to help meet health departments' unique needs and support unanticipated events that could require the diversion of resources to specific emerging or reemerging diseases.

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To aid decision-making during CDC's response to the 2014-2016 Ebola virus disease (Ebola) epidemic in West Africa, CDC activated a Modeling Task Force to generate estimates on various topics related to the response in West Africa and the risk for importation of cases into the United States. Analysis of eight Ebola response modeling projects conducted during August 2014-July 2015 provided insight into the types of questions addressed by modeling, the impact of the estimates generated, and the difficulties encountered during the modeling. This time frame was selected to cover the three phases of the West African epidemic curve.

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Objective: This study assessed the usefulness of the Healthy Weight Disparity Index (HWDI) to evaluate income disparities related to obesity. We compared state based body mass index (BMI) rankings with HWDI rankings.

Methods: National data from the 2010 Behavioral Risk Factor Surveillance System were used to estimate mean BMI levels in each of the 50 states (plus Washington, D.

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