Publications by authors named "Leadisaelle Hosanna Lenguiya"

Article Synopsis
  • * Researchers found that 4 out of 163 tested wild ruminants were positive for RVFV, with a genetic link to a virus from Namibia, indicating RVF's presence in Gabon's wildlife.
  • * In a separate survey of 306 domestic animals, they found 15.4% had RVFV-specific antibodies, predominantly in goats, emphasizing the need for improved surveillance and control measures for RVF in the region.
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Article Synopsis
  • - Coronaviruses are a diverse group of viruses that can infect various animals, including humans, with some strains like SARS-CoV-1, SARS-CoV-2, and MERS-CoV affecting global health significantly and originating from bats through intermediary hosts.
  • - A study in Gabon screened 229 faecal samples from wild great apes and mandrills for coronaviruses using nested PCR, but all samples tested negative for CoVs.
  • - The negative results might be due to a small sample size, the temporary nature of infections, or the unsuitability of faecal samples for detection, indicating the need for future studies using larger sample sizes and alternative non-invasive methods to better understand CoV circulation
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Article Synopsis
  • - The study focused on screening astroviruses (AstVs), enteroviruses (EVs), and caliciviruses (CaVs) in domestic animals to understand their potential to spread zoonotic diseases in rural Central Africa, where these animals interact closely with wildlife.
  • - Researchers collected rectal swabs from 123 goats, 41 sheep, and 76 dogs across 10 villages in northeastern Gabon, using PCR to detect various viruses by amplifying specific genes.
  • - Out of 240 samples, 23 tested positive for the viruses, with the majority found in goats, and some sequences clustering with known viruses that could pose a risk to humans, suggesting these animals could harbor pathogens that affect human health.
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Following the emergence of SARS-CoV-2, cases of pets infected with variants circulating among humans were reported. In order to evaluate the occurrence of SARS-CoV-2 circulation among pets in the Republic of the Congo, we conducted a ten-month study of dogs and cats living in COVID-19-positive households in Brazzaville and neighboring localities. Real-time PCR and the Luminex platform were used to detect SARS-CoV-2 RNA and antibodies to SARS-CoV-2 RBD and S proteins, respectively.

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To determine when severe acute respiratory syndrome coronavirus 2 arrived in Congo, we retrospectively antibody tested 937 blood samples collected during September 2019-February 2020. Seropositivity significantly increased from 1% in December 2019 to 5.3% in February 2020, before the first officially reported case in March 2020, suggesting unexpected early virus circulation.

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