Publications by authors named "Lea Zachau"
Background: Split liver transplantation is still discussed controversially. Utilization of split liver grafts has been declining since a change of allocation rules for the second graft abolished incentives for German centres to perform ex situ splits. We therefore analysed our long-term experiences with the first ex situ split liver transplant series worldwide.
View Article and Find Full Text PDFBackground: This retrospective, single-center, observational study on postoperative long-term results aims to define yet unknown factors for long-term outcome after operation for chronic pancreatitis.
Patients And Methods: We analyzed 147 consecutive patients operated for chronic pancreatitis from 2000 to 2011. Mean follow-up was 5.
The goal of this study was the characterization of long-term cancer risks after liver transplantation (LT) with implications for prevention and detection. Site-specific cancer incidence rates and characteristics were compared retrospectively for 2000 LT patients from a single institution (January 1, 1983 to December 31, 2010) and the general German population with standardized incidence ratios (SIRs); the total follow-up at December 31, 2011 was 14,490 person-years. The cancer incidence rates for the LT recipients were almost twice as high as those for the age- and sex-matched general population (SIR = 1.
View Article and Find Full Text PDFArticle Synopsis
- The study examines how effective different scoring models (DRI, ECD-score, D-MELD-score) are in predicting early outcomes after liver transplants using data from 291 procedures.
- Findings reveal that these models show low accuracy (AUROCs <0.7) in forecasting 30-day mortality and other key survival metrics, indicating poor overall reliability.
- The conclusion suggests that the current models do not adequately predict short-term outcomes in liver transplantation within a European context, highlighting the need for better predictive tools.
Background: The SOFT-score, P-SOFT-score, SALT-score and labMELD-score have been applied for the prediction of survival of liver transplant recipients after transplantation. We analysed the value of these scores for the prediction of short-term survival in high-risk liver transplant recipients with a labMELD-score ≥30.
Material/methods: Retrospective single-centre analysis including 88 consecutive liver transplants in adults between 01.