Publications by authors named "Lea Scharlemann"
Article Synopsis
- A study evaluated whether giving heparin before arriving at the hospital improves outcomes for patients with suspected non-ST segment elevation acute coronary syndrome (NSTE-ACS).
- The research included 1,234 patients from 2013 to 2021, comparing those who received pre-hospital heparin to those who did not, using statistical methods to analyze mortality rates after 30 days and one year.
- Results showed no significant difference in mortality rates between the groups and low rates of bleeding, suggesting that pre-hospital heparin may not be beneficial for this type of patient and should be used more cautiously.
Background: While left bundle branch block (LBBB) is a well-known risk feature in patients with acute myocardial infarction, and a rapid invasive management is recommended, data supporting this strategy for patients with right bundle branch block (RBBB) is less robust.
Methods: In total, 2139 patients with suspected ST-elevation myocardial infarction (STEMI) were triaged to acute coronary angiography based on a prehospital 12-lead electrocardiogram (ECG). Sensitivity and specificity for STEMI-ECG criteria were compared in RBBB and non-BBB patients.
Background: Emergency departments worldwide are increasingly adopting rapid diagnosis of patients with suspected myocardial infarction (MI) based on high-sensitivity troponin. We set out to assess the diagnostic accuracy of a high-sensitivity cardiac troponin I (hs-cTnI) assay in a prospective study.
Methods: In a cohort study including 1800 patients presenting with suspected acute MI, we developed and temporally validated a 0/1 h diagnostic algorithm using the Siemens Atellica IM hs-cTnI assay.