Publications by authors named "Lea Razakamanantsoa"

Article Synopsis
  • In a study on chronic respiratory failure patients using home non-invasive ventilation (NIV), researchers investigated the prevalence and impact of side effects caused by masks, finding that 47% of patients experienced moderate to severe issues.
  • The research indicated that patients with oronasal masks reported more severe side effects compared to those using nasal masks, which were also found to be more stable in a bench study.
  • The findings suggest that mask-related issues can negatively affect patients' daytime carbon dioxide levels, sleep quality, and overall quality of life, recommending nasal masks as a preferable option.
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The Respiratory Intensive Care Assembly of the European Respiratory Society gathered in Berlin to organise the second Respiratory Failure and Mechanical Ventilation Conference in June 2022. The conference covered several key points of acute and chronic respiratory failure in adults. During the 3-day conference, ventilatory strategies, patient selection, diagnostic approaches, treatment and health-related quality of life topics were addressed by a panel of international experts.

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Background And Objective: When home non-invasive ventilation (NIV) is initiated, five goals need to be achieved: a daily use >4 h/day, an improvement in gas exchange, health-related quality of life (HRQL) and sleep quality without side effects. Our aim was to assess how frequently these five goals were reached and the factors predictive of achievement.

Methods: We conducted a monocentric cohort study that included patients electively established on home NIV over 2 years.

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Article Synopsis
  • SARS-CoV-2 aerosolization during noninvasive ventilation can pose risks to healthcare professionals, leading to the exploration of various circuit setups aimed at reducing aerosol spread while maintaining ventilator performance.
  • The study tested eight different circuit setups using a model to assess their effects on ventilator efficacy during noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) by measuring various performance variables.
  • Results revealed that circuit type significantly affected key ventilator performance metrics, with the dual-limb circuit and oronasal mask setup providing the best performance and a single-limb circuit setup yielding the worst results.
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