Publications by authors named "Lea Goethals"
J Immunol Methods
November 2024
Article Synopsis
- A study was conducted to compare a modified radioimmunoassay (RIA) kit to two enzyme-linked immunosorbent assays (ELISA) methods for detecting anti-acetylcholine receptor (AChR) antibodies in a mouse model of myasthenia gravis (MG).
- The modified RIA showed high sensitivity (84.1%) and perfect specificity (100%), indicating its effectiveness in identifying AChR antibodies.
- The results suggest that using this modified RIA kit could streamline the antibody quantification process and minimize variability across different labs, as it doesn’t require time-consuming and costly antigen purification.
