Publications by authors named "Lea Fornero"

Article Synopsis
  • - The case involves a patient with severe thrombocytosis, where no secondary causes were identified, and although there were no signs of myelofibrosis, the patient's megakaryocytes were notably small and abnormal.
  • - Genetic analysis revealed a novel calreticulin (CALR) mutation (C105S), alongside mutations in ASXL1, U2AF1, and EZH2, all found in myeloid cells, leading to a diagnosis of myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN).
  • - Treatment with hydroxycarbamide was initiated due to high thrombosis risk, but as the patient's condition worsened, additional mutations (SETBP
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Introduction: Rituximab monotherapy represents the main therapeutic option for cryoglobulinemic vasculitis (CV) with severe organ involvement. However, initial worsening of the CV, known as rituximab-associated CV flare (=CV flare), has been described and are associated with high mortality rates. The aim of the present study is to evaluate the outcomes of plasmapheresis initiated before or during rituximab treatment, as prevention of CV flare.

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