Publications by authors named "Lea Epstein"
Background: Inconsistent findings exist regarding long-term substance use (SU) risk for children diagnosed with attention-deficit/hyperactivity disorder (ADHD). The observational follow-up of the Multimodal Treatment Study of Children with ADHD (MTA) provides an opportunity to assess long-term outcomes in a large, diverse sample.
Methods: Five hundred forty-seven children, mean age 8.
Article Synopsis
- The study aimed to investigate whether the atypical antipsychotic risperidone causes cognitive blunting in children undergoing treatment for attention-deficit/hyperactivity disorder (ADHD) and severe physical aggression.
- A total of 165 children participated, with assessments of attention and memory conducted before and after different treatment regimens over nine weeks.
- Results showed initial improvements in attention and memory after stimulant treatment, but no significant difference in performance between the risperidone and placebo groups after combined treatment, suggesting no negative impact from short-term risperidone use on these cognitive functions.
Blood group antigen expression in dysplasia and adenocarcinoma of the prostate.
Am J Surg Pathol
September 1990
Blood group antigens have been implicated as markers in oncogenesis; however, studies of blood group antigen expression in the prostate have yielded conflicting data. This study examined the expression of A, B, H, X, and Lewis antigens in 30 prostates removed for adenocarcinoma, by utilizing monoclonal antibodies, Ulex europaeus agglutinin I (for H type-2 chains), and the secretor status. A, B, and Ulex staining of the normal prostate most commonly demonstrated strong straining of 5-15% of cells.
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