Exercise training alone or in combination with high-protein diet in patients with late onset Pompe disease: results of a cross over study.

Background: Late onset Pompe disease (LOPD) is a lysosomal neuromuscular disorder which can progressively impair the patients' exercise tolerance, motor and respiratory functions, and quality of life. The available enzyme replacement therapy (ERT) does not completely counteract disease progression. We investigated the effect of exercise training alone, or associated with a high-protein diet, on the exercise tolerance, muscle and pulmonary functions, and quality of life of LOPD patients on long term ERT.

Changes in Skeletal Muscle Oxidative Capacity After a Trail Running Race.

Purpose: to evaluate the effects of a trail-running race on muscle oxidative function by measuring pulmonary gas exchange variables and muscle fractional O extraction.

Methods: Eighteen athletes were evaluated before (PRE) and after (POST) a trail running competition of 32-km or 50-km with 2000 m or 3500 m of elevation gain, respectively. During the week before the race, runners performed an incremental uphill running test and an incremental exercise by utilizing a one-leg knee-extension (KE) ergometer.

Aging effects on prefrontal cortex oxygenation in a posture-cognition dual-task: an fNIRS pilot study.

Background: The aging process alters upright posture and locomotion control from an automatically processed to a more cortically controlled one. The present study investigated a postural-cognitive dual-task paradigm in young and older adults using functional Near-Infrared Spectroscopy (fNIRS).

Methods: Twenty healthy participants (10 older adults 72 ± 3 y, 10 young adults 23 ± 3 y) performed a cognitive (serial subtractions) and a postural task (tandem stance) as single-tasks (ST) and concurrently as a dual-task (DT) while the oxygenation levels of the dorsolateral prefrontal cortex (DLPFC) were measured.

Short-Term Effects of Rolling Massage on Energy Cost of Running and Power of the Lower Limbs.

Purpose: Self-myofascial release (SMFR) is a type of self-massage that is becoming popular among athletes. However, SMFR's effects on running performance have not yet been investigated. The aim of this study was to evaluate the effects of SMFR on the cost of running (Cr).