Publications by authors named "Le-Le Deng"
Article Synopsis
- Ethylene response factors play a key role in plant development and stress tolerance, with this study focusing on the regulatory effects of the NtERF10 gene on tobacco plant height.
- Researchers compared a gene-edited tobacco mutant (ERF10-KO) with wild-type plants, analyzing gene expression and metabolite levels to understand how NtERF10 influences growth.
- The study identified over 4,000 differentially expressed genes and highlighted key genes and transcription factors involved in photosynthesis, hormone signaling, and other pathways, offering insights for molecular breeding in tobacco.
Article Synopsis
- Tuberculosis (TB) remains a significant public health challenge in China, with a study analyzing TB incidence from 2014 to 2021 to better understand its epidemiology and inform prevention strategies.
- The research utilized a sophisticated two-stage distributed lag nonlinear model to assess the influence of meteorological factors on TB rates, alongside demographic, healthcare, and economic factors using spatial panel data models.
- Findings revealed a decrease in TB incidence from 67.05 to 46.40 cases per 100,000 from 2014 to 2021, with higher rates among males, farmers, and older adults, as well as a notable impact from specific meteorological conditions on TB risk.
Article Synopsis
- The study examines the incidence of seven respiratory infectious diseases (RIDs) in mainland China from 2017 to 2021 to improve public health strategies.
- A total of 11,963,886 cases were reported, with seasonal influenza having the highest average incidence rate, and males showed higher rates across all diseases.
- Notably, tuberculosis rates were highest among farmers and those over 65, while other RIDs affected mostly children; incidences of PTB and measles declined, whereas the other RIDs peaked in 2019.
Article Synopsis
- The study investigates the genotyping features of human fecal strains and the link between antibiotic resistance genes (ARGs) and multidrug resistance (MDR) in a Beijing district known for high rates of infectious diarrhea.
- Over three years, researchers isolated 94 strains from fecal samples, assessing antibiotic susceptibility and analyzing genetic data through whole-genome sequencing.
- Findings showed a high prevalence of MDR among the isolates, with similar rates in both diarrheal and healthy individuals, and the study suggests ongoing monitoring of ARGs and MDR is necessary for improving predictions and understanding the transmission of resistance genes.
Background: Ethionamide (ETH), a structural analogue of isoniazid (INH), is used for treating multidrug-resistant tuberculosis (MDR-TB). Due to the common target InhA, INH and ETH showed cross-resistance in . This study aimed to explore the INH and ETH resistant profiles and genetic mutations conferring independent INH- or ETH-resistance and INH-ETH cross-resistance in circulating in south of Xinjiang, China.
View Article and Find Full Text PDF[Main Infection Control Measures for Respiratory Infectious Diseases in Medical Institutions and Public Places in China].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2023
Article Synopsis
- Respiratory infectious diseases (RID) pose significant public health threats, and effective infection control (IC) is crucial for managing their spread.
- A review of literature since 2018 highlighted achievements, problems, and challenges in IC across various levels of medical institutions in China, showing inconsistent efforts in different regions.
- Recommendations include better application of existing IC tools, the development of advanced technology for new IC products, and the establishment of a digital platform for monitoring and managing infections to enhance IC measures.
Article Synopsis
- The study investigates how globalization and increased international travel contribute to the importation of respiratory infectious diseases (RIDs) in China, using data from 2014 to 2018.
- It found that over 31,000 cases of imported RIDs were reported during this period, mostly comprised of influenza, with a notable increase in incidence rates over the years.
- The findings highlight the need for enhanced surveillance and high-tech methods to detect and prevent the spread of imported RIDs to safeguard public health in China.