Publications by authors named "Le-Hua Cheng"

Background: Long noncoding RNAs (lncRNAs) are a class of ubiquitous noncoding RNAs and have been found to act as tumor suppressors or oncogenes, which dramatically altered our understanding of cancer. Naked mole rat (NMR, ) is an exceptionally long-lived and cancer-resistant rodent; however, whether lncRNAs play roles in cancer resistance in this seductive species remains unknown.

Results: In this study, we developed a pipeline and identified a total of 4422 lncRNAs across the NMR genome based on 12 published transcriptomes.

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Article Synopsis
  • The compound C(35)H(30)N(2)S(3) was created through a solvent-free reaction method.
  • The molecule has an E,E configuration, positioning the benzene and pyrimidine rings on opposite sides of the carbon-carbon double bonds.
  • π-π stacking was observed between the nearly parallel pyrimidine and benzene rings of neighboring molecules, with a centroid-centroid separation of 3.5808 Å.
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