Angiotensin-converting enzyme I/D polymorphism and aortic aneurysm risk: a meta-analysis.

Objectives: Angiotensin-converting enzyme (ACE) I/D polymorphism has been implicated in aortic aneurysm risk, but individual published studies show inconclusive results. The aim of this study was to explore a more precise estimation of its relation with aortic aneurysm using meta-analysis.

Methods: Electronic searches of PubMed and EMBASE databases were conducted for all publications through February 2014.