Publications by authors named "Le Xuan Luat"
An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal products can lead to acquisition of zoonotic pathogens, a number of which cause central nervous system (CNS) infections. However, studies show the aetiology of CNS infections remains unknown in around half of cases.
View Article and Find Full Text PDFBackground: Dengue is a mosquito-borne flavivirus present in many metropolitan cities of tropical countries.
Methods: During and after the dengue season (September 2018 to January 2019), we conducted a case-control study in order to determine the risk factors for dengue fever in Hanoi city, Vietnam. 98 dengue patients and 99 patients with other acute infections, such as Hepatitis B virus infection, were recruited at Department of Infectious Disease of Bach Mai national hospital in Hanoi.
Tick-borne encephalitis virus (TBEV) is a zoonotic agent that causes acute central nervous system (CNS) disease in humans. We previously suggested that immune response in addition to CNS infection contribute to mouse mortality following TBEV infection. However, we did not examine the influence of virus variants in the previous study.
View Article and Find Full Text PDFArticle Synopsis
- Echovirus 30 (E30) and Japanese encephalitis virus (JEV) are prevalent causes of acute meningitis in Southeast Asia, prompting a study to differentiate between them due to potential misdiagnosis, particularly during an outbreak in Vietnam (2001-2002).
- A retrospective study analyzed clinical records of 43 E30 and 60 JEV cases, comparing symptoms and clinical parameters using statistical methods.
- Results indicated that symptoms like fever, headache, and vomiting were common to both, but E30 cases showed a higher prevalence of headache and vomiting combinations, while JEV cases exhibited stronger neurological symptoms and distinct cerebrospinal fluid (CSF) profiles.