Utilization of Response Surface Methodology in Optimization of Polysaccharides Extraction from Vietnamese Red by Ultrasound-Assisted Enzymatic Method and Examination of Bioactivities of the Extract.

Red is a popular medicinal herb commonly used in Vietnamese traditional remedies due to its potential value for health. In this study, polysaccharides were extracted from using ultrasound-assisted enzymatic extraction method. The response surface methodology and Box-Behnken design were employed to investigate the effects of pH, extraction temperature, extraction time, and ultrasonic power on the content of polysaccharides.