Extreme Temperatures Reduce Copepod Performance and Change the Relative Abundance of Internal Microbiota.

Copepods are one of the most abundant invertebrate groups in the seas and oceans and are a significant food source for marine animals. Copepods are also particularly sensitive to elevated temperatures. However, it is relatively unknown how the internal microbiome influences copepod susceptibility to warming.

In silico identification of compounds from Roxb leaf fractionated extract inhibit interleukin-6 to prevent rheumatoid arthritis.

Medicinal herbs with a phytonutrient background has been applied globally as major alternatives to ameliorate the continuous increase in rheumatoid arthritis cases worldwide. We herein aimed to critically examine the bioactive components of the medicinal herb Piper sarmentosum Roxb leaf fractionated extract for its potential to inhibit the influx of interleukin-6 (IL-6) in rheumatoid arthritis. The Schrödinger platform was employed as the main computational acumen for the screening of bioactive compounds identified and reference compounds subjected to molecular simulation (MDS) for analyzing the stability of docked complexes to assess fluctuations and conformational changes during protein-ligand interactions.

Phytotherapeutic potential of compounds identified from fractionated extracts of L., as an inhibitor of interleukin-6 in the treatment of rheumatoid arthritis: computational approach.

The presence of HLA-DRB1 alleles that encode critical points associated with environmental interactions is associated with increased risk of rheumatoid arthritis caused by anti-citrullinated protein antibodies. Therefore, interleukin-6 (IL-6), a multifunctional cytokine that controls both local and systemic acute inflammatory responses through its ability to induce a phase response, plays a serious role. Its overexpression leads to pathological challenges such as rheumatoid arthritis and menopausal osteoporosis.

Dataset on the compounds from the leaves of Vietnamese and their anti-inflammatory activity.

has a history of traditional applications including treating dyspepsia, apoplexy, headaches, abdominal pain, abdominal distension, and leg edema [1]. It is also employed for alleviating allergies, inflammation, pain relief, promoting blood circulation, addressing costal chondritis, and sinusitis [2]. Research into the chemical composition of has revealed the presence of lignans, flavonoids, lactones, and essential oils [1,[3], [4], [5].

Transgenerational exposure to marine heatwaves ameliorates the lethal effect on tropical copepods regardless of predation stress.

Marine heatwaves (MHWs) are emerging as a severe stressor in marine ecosystems. Extreme warm sea surface temperatures during MHWs often exceed the optimal thermal range for more than one generation of tropical coastal zooplankton. However, it is relatively unknown whether transgenerational plasticity (TGP) to MHWs may shape the offspring's fitness, particularly in an ecologically relevant context with biotic interactions such as predation stress.

A Variable-Length Chromosome Genetic Algorithm for Time-Based Sensor Network Schedule Optimization.

Scheduling sensor nodes has an important role in real monitoring applications using sensor networks, lowering the power consumption and maximizing the network lifetime, while maintaining the satisfaction to application requirements. Nevertheless, this problem is usually very complex and not easily resolved by analytical methods. In a different manner, genetic algorithms (GAs) are heuristic search strategies that help to find the exact or approximate global optimal solution efficiently with a stochastic approach.

Parental exposures increase the vulnerability of copepod offspring to copper and a simulated marine heatwave.

Extreme temperatures from marine heatwaves (MHWs) and pollution are dominant stressors in tropical marine ecosystems. However, we know little about the role of transgenerational effects of metals and MHWs in shaping the offspring's vulnerability to these stressors. We addressed this fundamental knowledge gap by exposing the planktonic copepod Pseudodiaptomus incisus to copper (Cu: control, 15 and 60 μg L) under 2 temperatures (30 and a simulated marine heatwave at 34 °C) in the first generation (F1) and 16 treatments in F2: offspring from each of 4 F1 conditions (control or 15 μg Cu L × 30 or 34 °C) was reared in 4 F2 conditions (control or 15 μg Cu L × 30 or 34 °C).

Interactive effects of extreme temperature and a widespread coastal metal contaminant reduce the fitness of a common tropical copepod across generations.

Tropical coastal areas are increasingly exposed to temperature extremes from marine heatwaves and contaminants from anthropogenic activities. The interactive effects of these environmental changes on marine life are understudied. We investigated the direct and cross-generational effects of copper (Cu) on F0 and F1 generations of the common tropical copepod Pseudodiaptomus annandalei under extreme temperatures (30 and 34 °C).

New insights into the urban washoff process with detailed physical modelling.

Current urban washoff models still rely on empirical catchment-scale functions, that have not been substantially updated during the last 40years. This paper introduce a new approach using the physical model FullSWOF to evaluate urban washoff process. The modelling approach is performed for a Parisian road catchment.

A new approach of monitoring and physically-based modelling to investigate urban wash-off process on a road catchment near Paris.

Nowadays, the increasing use of vehicles is causing contaminated stormwater runoff to drain from roads. The detailed understanding of urban wash-off processes is essential for addressing urban management issues. However, existing modelling approaches are rarely applied for these objectives due to the lack of realistic input data, unsuitability of physical descriptions, and inadequate documentation of model testing.

Evaluation of extenders and cryoprotectants on motility and morphology of longtooth grouper (Epinephelus bruneus) sperm.

The objective was to evaluate various extenders and cryoprotectants on postthaw motility of longtooth grouper (Epinephelus bruneus) sperm, based on sperm motility ratio (SMR), sperm velocity (SV), and morphological damage after thawing. To evaluate the optimal cryoprotectant for cryopreservation of longtooth grouper sperm, semen was diluted in 0.3 M glucose extender containing one of four cryoprotectants (dimethyl sulfoxide, methanol, ethylene glycol, and glycerol [Gly]) at a final concentration of 10% or 20%, and then frozen in liquid nitrogen vapor (-76 °C for 3 minutes) before storage in liquid nitrogen.

Effects of varying dilutions, pH, temperature and cations on spermatozoa motility in fish Larimichthys polyactis.

The objectives of this present study were to assess the effects of varying dilutions, pH, temperature and cations on spermatozoa motile parameters (SMPs) in fish Larimichthys polyactis. Optimal SMPs were observed when emen was diluted in artificial seawater (ASW) at a ratio of 1 to 100, with temperature of 10 degreesC and pH 8.0.