Primary Central Nervous System Lymphoma (PCNSL) - A Rare and Unusual Presentation of Rapidly Progressive Major Cognitive Dysfunction.

Primary central nervous system lymphoma (PCNSL) is a rare, extranodal non- Hodgkin's lymphoma confined to craniospinal axis. PCNSL accounts for less than 5% of all primary CNS malignancies and 1 to 2% of all lymphomas. Amongst the causes of major cognitive dysfunction, primary brain tumor exists as a less frequent cause.

Methyl alcohol poisoning: a manifestation of typical toxicity and outcome.

Methyl alcohol poisoning is an uncommon but an extremely hazardous poisoning. It most commonly occurs via oral ingestion of illicit or adulterated liquors or as ethanol substitution. The clinical diagnosis is made in the presence of high index of suspicion of toxic alcohol ingestion, early visual symptoms, unexplained anion gap metabolic acidosis and significant osmolar gap.