Publications by authors named "Lawrence Y Lu"

Median arcuate ligament syndrome (MALS) is an uncommon condition characterized by the compression of the celiac trunk by the median arcuate ligament. Due to the anatomical proximity to the foregut, MALS has significant implications in hepato-pancreato-biliary (HPB) surgery. It can pose complications in pancreatoduodenectomy and orthotopic liver transplantation, where the collateral arterial supply from the superior mesenteric artery is often disrupted.

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Guidelines for transcatheter aortic valve replacement (TAVR) antithrombotic prophylaxis are extrapolated predominantly from percutaneous coronary intervention (PCI) data. Here, we examined temporal coagulation changes occurring in the early perioperative period to determine the pathobiologic validity of this supposition. This was a prospective observational study of consecutive patients who underwent transfemoral TAVR (n = 27), PCI (n = 12), or surgical aortic valve replacement (SAVR) requiring cardiopulmonary bypass and cross-clamping (n = 12).

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Background: Influenza-associated pulmonary aspergillosis (IAPA) increasingly is being reported in critically ill patients. We conducted this systematic review and meta-analysis to examine the prevalence, risk factors, clinical features, and outcomes of IAPA.

Study Question: What are the prevalence, risk factors, clinical features, and outcomes of IAPA in critically ill patients?

Study Design And Methods: Studies reporting IAPA were searched in the following databases: PubMed MEDLINE, CINAHL, Cochrane Library, Embase, Scopus, Cochrane Trials, and ClinicalTrials.

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Article Synopsis
  • This study examined the impact of transfusing blood products that are close to their shelf-life on clinical outcomes in obstetric patients in Queensland, Australia, from 2007 to 2013.
  • Comparing fresh (less than 21 days old for RBC, less than 3 days for PLT) to old blood products (35 days or older for RBC, 4 days or older for PLT), researchers found no significant difference in patient outcomes such as hospital stay length or morbidity.
  • The results indicated that using older RBC or PLT did not lead to higher rates of complications or mortality among the patients studied.
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