A pilot in vivo study: potential ovarian cancer therapeutic by placental extracellular vesicles.

The biological links between cancer and pregnancy are of interest due to parallel proliferative, immunosuppressive, and invasive mechanisms between tumour and placental cells. However, the proliferation and invasion of placental cells are strictly regulated. The understanding of this regulation is largely unknown.

Lipiodol alters murine uterine dendritic cell populations: a potential mechanism for the fertility-enhancing effect of lipiodol.

Objective: To determine whether treatment with lipiodol alters the leukocyte population in the uterus.

Design: Randomized controlled animal study.

Setting: University research laboratory.

Human seminal plasma prolactin-inducible protein is an immunoglobulin G-binding protein.

Antisperm antibodies (ASA) are present in 20% of couples seeking treatment for infertility. Antibody-binding proteins in seminal plasma may protect sperm from ASA-induced damage. We have previously isolated several IgG-binding proteins from human seminal plasma using IgG affinity chromatography.