Publications by authors named "Lawrence V Larsen"
Background: A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR).
Objective: To evaluate the safety and efficacy of 2 concentrations of olopatadine nasal spray vs placebo in patients with SAR.
Methods: This was a multicenter, randomized, double-blind, placebo-controlled study.
Formoterol provides long-lasting protection against exercise-induced bronchospasm.
Ann Allergy Asthma Immunol
October 2002
Background: Patients with exercise-induced bronchospasm (EIB) may benefit from a prophylactic beta2-adrenergic agonist that combines rapid onset with long duration of action.
Objective: To compare the protective effect against EIB of a single inhaled dose of formoterol powder delivered via the Aerolizer inhaler (Novartis Pharmaceuticals, East Hanover, NJ) with the effect of placebo and albuterol.
Methods: Eighteen patients with EIB were randomized to treatment in a double-blind, placebo-controlled, four-way, crossover study.