Publications by authors named "Lawrence V Friedrich"
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Synopsis of recent research by authors named "Lawrence V Friedrich"
- Lawrence V Friedrich's recent research primarily focuses on the pharmacokinetics and pharmacodynamics (PK-PD) of β-lactamase inhibitors in combination with various β-lactam antibiotics, aiming to optimize treatment strategies against resistant bacterial pathogens.
- His studies utilize in vitro infection models to evaluate the effectiveness and dosing regimens of novel inhibitors like CB-618 and the combination of tazobactam with ceftolozane, providing crucial insights into their efficacy against different strains of antibiotic-resistant bacteria, especially Escherichia coli.
- Friedrich's work emphasizes the need for understanding drug exposure relationships to combat the amplification of antibiotic resistance, offering valuable data that can inform clinical practices and the development of new therapeutic approaches.
