Publications by authors named "Lawrence Nadin"
Background: During the COVID-19 pandemic, France faced a 2-month lockdown in 2020, marked by numerous restrictions. This study aimed to examine the experience and management of children aged 6-17 years with learning and/or attention disorders during the first lockdown.
Methods: We conducted an observational, retrospective study, with data collection from March 1 to May 31, 2021, by means of an anonymous digital qualitative questionnaire completed by parents.
Article Synopsis
- Ruptured middle cerebral artery aneurysms (MCAa) can cause serious brain bleeding (intracerebral hematoma), and the study aimed to compare the outcomes of two treatments: microsurgery (clipping) and endovascular therapy (EVT).
- The research involved 162 adult patients who needed evacuation of intracerebral hematoma across nine hospitals in France, analyzing factors linked to recovery using a standard scale (modified Rankin scale) after six months.
- Results showed that clipping was associated with better functional outcomes (30% poor outcome rate) compared to EVT (76% poor outcome rate), potentially due to longer delays in treatment for the EVT group.
Background: Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are rare, aggressive cutaneous T-cell lymphomas that may be difficult to treat. Mogamulizumab is a recent monoclonal antibody targeting the CCR4 receptor expressed on the surface of Sézary cells. It can be prescribed in MF/SS stages III to IV in the second line after systemic therapy or in stages IB-II after two unsuccessful systemic therapies.
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