Publications by authors named "Lawrence M White"

Background: Peritumoral edema on staging magnetic resonance imaging (MRI) is associated with higher local recurrence in soft tissue sarcoma (STS). This may relate to the presence of satellite malignant cells that are difficult to distinguish from benign atypia, leading to over- or undertreatment. This study evaluated a novel targeted molecular approach to identify malignancy in STS peritumoral planes as a means to improve personalized care.

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  • The study aimed to assess the incidence and characteristics of CT imaging findings in adults with extremity soft tissue infections before and during the COVID-19 pandemic.
  • It involved analyzing 213 CT exams from the pre-COVID period and 383 from the COVID period, revealing similar demographics but a significant increase in serious findings during the pandemic.
  • The research highlights a rise in both the number and severity of soft tissue infections in emergency departments during COVID-19, suggesting changes in healthcare delivery and patient behavior that could influence future pandemic responses.
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  • Whole-body MRN is being studied as a way to detect changes in peripheral nerves of patients with CIDP and to monitor responses to immunotherapy in those who haven't been treated before.
  • In the study, MRN revealed notable thickening and increased signal intensity in nerves of five out of eight patients diagnosed with CIDP, while these changes were not present in healthy controls.
  • The results suggest that MRN is a promising tool for identifying nerve abnormalities in CIDP, but future research should look at longer follow-up periods post-treatment for a better assessment of its effectiveness.
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Ankle fractures involving the distal fibula are common injuries. Malreductions and subsequent malunions of the distal fibula can result in worse clinical outcomes and posttraumatic arthritis. The ability to accurately evaluate and identify malreductions and malunions of the distal fibula is important.

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Sarcomas are heterogeneous rare tumors predominantly affecting the musculoskeletal (MSK) system. Due to significant variations in their natural history and variable response to conventional treatments, the discovery of novel diagnostic and prognostic biomarkers to guide therapeutic decision-making is an active and ongoing field of research. As new cellular, molecular, and metabolic biomarkers continue to be discovered, quantitative radiologic imaging is becoming increasingly important in sarcoma management.

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  • Wheelchair basketball (WCB) players often suffer shoulder injuries, yet there is limited understanding and literature about the specifics of these injuries within this para-sport.
  • A study reviewed MRI evaluations of 28 elite WCB athletes to identify injury patterns related to the shoulder, focusing on various shoulder components including the rotator cuff and labrum.
  • Results showed high instances of supraspinatus and infraspinatus tears, alongside correlations between injury severity and factors like low IWBF classification and limited trunk control among the athletes.
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Introduction: Computed tomography (CT) is often utilized for both diagnostic and pre-operative planning purposes in shoulder arthroplasty. Our study reports on the incidence of pulmonary findings in our pre-operative shoulder arthroplasty population over 14 years at our institution.

Methods: We conducted a retrospective review of all "shoulder CT" exams ordered by two orthopedic upper extremity surgeons between the years of 2008 and 2021.

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Objective: To analyze radiomic features obtained from pre-treatment T2-weighted MRI acquisitions in patients with histologically proven intramedullary high-grade osteosarcomas and assess the accuracy of radiomic modelling as predictive biomarker of tumor necrosis following neoadjuvant chemotherapy (NAC), overall survival (OS), and disease-free survival (DFS).

Materials And Methods: Pre-treatment MRI exams in 105 consecutive patients who underwent NAC and resection of high-grade intramedullary osteosarcoma were evaluated. Histologic necrosis following NAC, and clinical outcome-survival data was collected for each case.

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Meniscal tears are one of the most common knee injuries. Partial meniscectomy and meniscal repair are the most common treatment options in the setting of an unstable meniscal tear. Standard MR diagnostic criteria of a meniscal tear may be normal findings postoperatively.

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Benign primary bone tumors are far more common than their malignant counterpart and are encountered in everyday practice. Imaging plays a crucial role in recognition of the nonaggressive nature of these lesions, determining the need for further imaging or follow-up. This article reviews the clinical, demographic, and radiological features of some of the more common entities classified as benign or intermediate (locally aggressive) according to the World Health Organization classification of bone tumors.

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Objective: To assess the accuracy of routine knee MRI in detecting acute popliteal artery and/or common peroneal nerve (CPN) dysfunction following multiligamentous knee injury (MLKI), with correlation of MRI findings to clinical outcome.

Materials And Methods: Routine MRI knee examinations in 115 MLKI patients (54/115 with acute neurovascular injury, 61/115 without neurovascular injury) were retrospectively reviewed. Cases were classified by injury mechanism and ligamentous injuries sustained.

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Objective: Solitary fibrous tumors (SFTs) uncommonly occur in the musculoskeletal system, with limited available data on their MRI appearance. This study was performed to assess the MRI features of SFTs in the musculoskeletal system (MSK-SFTs).

Materials And Methods: Pre-treatment MRI in 39 patients with pathologically proven SFTs in the trunk or extremities was evaluated.

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Objectives: To review the clinical and imaging findings of patients with remote history of intramuscular (IM) in vitro fertilization (IVF) gluteal injections, presenting with signs and symptoms of a possible gluteal soft tissue sarcoma.

Methods And Methods: Retrospective review of consecutive patients with a history of prior IVF therapy referred for MRI evaluation of a gluteal soft tissue mass was performed. Six patients were reviewed, with 5 patients meeting study inclusion criteria.

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Purpose: To assess the accuracy and reliability of routine preoperative magnetic resonance imaging (MRI) in the detection of the comma sign compared with the gold standard of arthroscopic findings.

Methods And Materials: Preoperative MRI exams in consecutive patients undergoing arthroscopic subscapularis tendon repair, over a 5-year time frame, were retrospectively reviewed for full-thickness tears of the subscapularis and supraspinatus tendons, fatty atrophy of the subscapularis and supraspinatus muscles, and status of the long head of the biceps tendon. Each case was also evaluated for presence or absence of a comma sign on MRI.

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Purpose: To highlight the spectrum of pathology and patterns of gluteus minimus tendon tearing observed on MR imaging of the hip.

Methods And Materials: Retrospective review of consecutive hip MRI exams with findings of gluteus minimus tendon (GMin) pathology. A total of 194 exams in 178 patients (148 female, mean age 61) were reviewed.

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Background: Acromioclavicular joint (ACJ) injuries are common in ice hockey players and are traditionally evaluated with conventional radiography, which has recognized limitations in the accurate characterization of the spectrum of soft tissue injuries and severity/grade of injury sustained.

Purpose: To evaluate the epidemiologic, clinical, and magnetic resonance imaging (MRI) findings in professional ice hockey players who have sustained acute ACJ injuries.

Study Design: Case series; Level of evidence, 4.

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Background: Hockey players sustain a greater incidence of ankle syndesmosis injuries than other athletes. These injuries have a higher morbidity and more unpredictable recovery than lateral ankle sprains. Magnetic resonance imaging (MRI) has been used to establish the diagnosis but has not been evaluated for its ability to predict return to play.

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Background: Desmoid fibromatosis (DF) is a rare fibroblastic proliferation that was historically treated with surgery. We report (a) outcomes using low-dose chemotherapy, methotrexate (MTX), and vinorelbine (VNL) for patients with progressing disease (PD) and (b) whether tumor volume (V ) and T2 signal on magnetic resonance imaging (MRI) are more reflective of treatment response compared with maximum tumor dimension (D ) defined by RECIST1.1.

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Objective: To augment the educational resources available to training programs and trainees in musculoskeletal (MSK) radiology by creating a comprehensive series of Web-based open-access core curriculum lectures.

Materials And Methods: Speakers with recognized content and lecturing expertise in MSK radiology were invited to create digitally recorded lecture presentations across a series of 42 core curriculum topics in MSK imaging. Resultant presentation recordings, organized under curriculum subject headings, were archived as open-access video file recordings for online viewing on a dedicated Web page (http://radiologycorelectures.

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Magnetic resonance imaging (MRI) represents the preferred noninvasive imaging technique to diagnose meniscal pathology in the pre- and postoperative setting. Furthermore, characterization of meniscal tissue MR properties has been possible by the development of advanced MRI techniques. Suspected meniscal tears are a frequent indication for MRI and the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) classification system has been developed to facilitate accurate and uniform reporting of such meniscal tears.

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Objective: The purpose of this article is to review current and emerging techniques and strategies that can be used to accelerate acquisition times in routine knee MRI.

Conclusion: Specific techniques reviewed include 3D fast spin-echo imaging as well as new approaches to rapid image acquisition techniques (parallel imaging, compressed sensing, simultaneous multislice, and neural network reconstruction techniques) and their potential application to knee MRI.

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Objective: To investigate the accuracy of non-arthrographic 3-T MRI compared to hip arthroscopy in the assessment of labral and cartilaginous pathology in patients with suspected FAI.

Materials And Methods: Following IRB approval and waived consent, 42 consecutive cases of suspected FAI with non-arthrographic 3-T MRI and arthroscopy of the hip were reviewed. High-resolution TSE MR imaging was evaluated in consensus by two musculoskeletal radiologists, blinded to arthroscopic findings, for the presence of labral tears and articular cartilage lesions.

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