Dose Measurements at Provision Proton Therapy Center.

Proton therapy is an advanced method for treating cancerous tumors, and its adoption has expanded significantly in recent years. The production of high-energy protons, however, may result in the creation of secondary neutrons and gamma rays. Hence, ensuring radiation safety at proton therapy centers is crucial, with shielding playing a vital role.

Advances in space radiation physics and transport at NASA.

The space radiation environment is a complex mixture of particle types and energies originating from sources inside and outside of the galaxy. These environments may be modified by the heliospheric and geomagnetic conditions as well as planetary bodies and vehicle or habitat mass shielding. In low Earth orbit (LEO), the geomagnetic field deflects a portion of the galactic cosmic rays (GCR) and all but the most intense solar particle events (SPE).

Reactor production of promethium-147.

In this paper, we describe the Pm production yields and level of impurities from several targets that consisted of milligram quantities of highly enriched Nd oxide irradiated at the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory for durations ranging from 24 to 180 h. A comparison between theoretical and experimental data are also presented, and attempts were made to empirically evaluate the neutron capture cross-sections of 41.3-d Pm and 5.

Simulation of the GCR spectrum in the Mars curiosity rover's RAD detector using MCNP6.

The paper presents results from MCNP6 simulations of galactic cosmic ray (GCR) propagation down through the Martian atmosphere to the surface and comparison with RAD measurements made there. This effort is part of a collaborative modeling workshop for space radiation hosted by Southwest Research Institute (SwRI). All modeling teams were tasked with simulating the galactic cosmic ray (GCR) spectrum through the Martian atmosphere and the Radiation Assessment Detector (RAD) on-board the Curiosity rover.

The radiation environment on the surface of Mars - Summary of model calculations and comparison to RAD data.

The radiation environment at the Martian surface is, apart from occasional solar energetic particle events, dominated by galactic cosmic radiation, secondary particles produced in their interaction with the Martian atmosphere and albedo particles from the Martian regolith. The highly energetic primary cosmic radiation consists mainly of fully ionized nuclei creating a complex radiation field at the Martian surface. This complex field, its formation and its potential health risk posed to astronauts on future manned missions to Mars can only be fully understood using a combination of measurements and model calculations.

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory.

Most accelerator-based space radiation experiments have been performed with single ion beams at fixed energies. However, the space radiation environment consists of a wide variety of ion species with a continuous range of energies. Due to recent developments in beam switching technology implemented at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL), it is now possible to rapidly switch ion species and energies, allowing for the possibility to more realistically simulate the actual radiation environment found in space.

Neutron yields and effective doses produced by Galactic Cosmic Ray interactions in shielded environments in space.

In order to define the ranges of relevant neutron energies for the purposes of measurement and dosimetry in space, we have performed a series of Monte Carlo transport model calculations that predict the neutron field created by Galactic Cosmic Ray interactions inside a variety of simple shielding configurations. These predictions indicate that a significant fraction of the neutron fluence and neutron effective dose lies in the region above 20 MeV up to several hundred MeV. These results are consistent over thicknesses of shielding that range from very thin (2.

Quality factors for space radiation: A new approach.

NASA has derived new models for radiological risk assessment based on epidemiological data and radiation biology including differences in Relative Biological Effectiveness for leukemia and solid tumors. Comprehensive approaches were used to develop new risk cross sections and the extension of these into recommendations for risk assessment during space missions. The methodology relies on published data generated and the extensive research initiative managed by the NASA Human Research Program (HRP) and reviewed by the National Academy of Sciences.

The response of a spherical tissue-equivalent proportional counter to different heavy ions having similar velocities.

A tissue-equivalent proportional counter (TEPC) has been used as a dosimeter in mixed radiation fields. Since it does not measure LET directly, the response function must be characterized in order to estimate quality factor and thus equivalent dose for the incident radiation. The objectives of this study were to measure the response of a spherical TEPC for different high-energy heavy ions (HZE) having similar velocity and to determine how quality factors can be determined.

The response of a spherical tissue-equivalent proportional counter to different ions having similar linear energy transfer.

The response of a tissue-equivalent proportional counter (TEPC) to different ions having a similar linear energy transfer (LET) has been studied. Three ions, 14N, 20Ne and 28Si, were investigated using the HIMAC accelerator at the National Institute of Radiological Sciences at Chiba, Japan. The calculated linear energy transfer (LET( infinity )) of all ions was 44 +/- 2 keV/microm at the sensitive volume of the TEPC.

Spatial distribution and yield of DNA double-strand breaks induced by 3-7 MeV helium ions in human fibroblasts.

Accelerated helium ions with mean energies at the target location of 3-7 MeV were used to simulate alpha-particle radiation from radon daughters. The experimental setup and calibration procedure allowed determination of the helium-ion energy distribution and dose in the nuclei of irradiated cells. Using this system, the induction of DNA double-strand breaks and their spatial distributions along DNA were studied in irradiated human fibroblasts.