Design optimization of intraoperative radiotherapy cones.

Purpose: Electron intraoperative cones (EIORCs) commonly used for intraoperative radiation therapy (IORT) often generate high-dose regions at superficial depths. This study was performed to optimize the use of rings in the EIORC design that reduces the high-dose region while minimizing the loss of the treatment volume at the prescribed depth.

Methods And Materials: Monte Carlo simulations were performed to study the dosimetry properties of various EIORC designs.