Publications by authors named "Lawrence F Jerome"
J Transl Med
November 2011
Article Synopsis
- - The study introduced new electrochemiluminescence (ECL) assays to detect insulin autoantibodies (IAA) and anti-insulin antibodies (IA), aiming to overcome the challenges of the traditional 125I-insulin radiobinding assay, which is inefficient and inconsistent across labs.
- - In tests using NOD mice and human samples, the ECL assays demonstrated quick results and high accuracy, effectively correlating IAA levels with diabetes onset and providing reliable measurements across different laboratories.
- - The researchers concluded that these innovative ECL assays could improve standardization and speed in detecting insulin antibodies, with plans to further evaluate the human IA assay in at-risk populations for type 1 diabetes.
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