How does evolutionary evaluation illuminate body size among canids?

In this review, we examine mammalian body size as it reflects life history and genomic composition, with a primary focus on canids and the domestication of the gray wolf. The range of variation in body size is greater among Carnivora than any other terrestrial order. In the Canidae, this range is some 2 orders of magnitude.

Integrating Navajo Pottery Techniques To Improve Silver Nanoparticle-Enabled Ceramic Water Filters for Disinfection.

Point-of-use treatment technologies can increase access to safe drinking water in rural areas. Sustained use of these technologies is uncommon due to oversight of community needs, user-perceived risks, long-term maintenance, and conflict with traditional practices. Nanosilver-enabled ceramic water filters are unique due to the use of locally sourced materials available at or near the target community; however, technical limitations persist (e.

Protozoan-Priming and Magnesium Conditioning Enhance Dissemination and Monochloramine Resistance.

Opportunistic pathogens (OPs) are of concern in drinking water distribution systems because they persist despite disinfectant residuals. While many OPs garner protection from disinfectants via a biofilm lifestyle, () also gains disinfection resistance by being harbored within free-living amoebae (FLA). It has been long established, but poorly understood, that grown within FLA show increased infectivity toward subsequent FLA or human cells (i.

Monitoring neural activity during sleep/wake events in adult C. elegans by automated sleep detection and stimulation.

Sleep in adult C. elegans occurs spontaneously, making timing of individual sleep/wake state transitions unpredictable. This protocol presents a closed-loop system to automatically detect sleep state transitions, trigger stimulation, and record evoked neural responses.

What would reduce caesarean section rates?-Views from pregnant women and clinicians in Ireland.

Background: Caesarean section rates continue to rise in most parts of the world. While CS is a lifesaving procedure there is evidence that, beyond a certain threshold, CS rates may contribute to increased maternal and perinatal morbidity. This study aimed to elicit the views of pregnant women's and clinicians' on how CS rates might be reduced.

Microfluidic Devices for Behavioral Analysis, Microscopy, and Neuronal Imaging in Caenorhabditis elegans.

Microfluidic devices offer several advantages for C. elegans research, particularly for presenting precise physical and chemical environments, immobilizing animals during imaging, quantifying behavior, and automating screens. However, challenges to their widespread adoption in the field include increased complexity over conventional methods, operational problems (such as clogging, leaks, and bubbles), difficulty in obtaining or fabricating devices, and the need to characterize biological results obtained from new assay formats.

Developmental features of the canid proximocaudal femur.

We continued direct morphological studies of the canid coxofemoral joint, considering early-life spatial relationships around the locus of the proximocaudal joint capsule insertion. Our primary goal was to elucidate the postnatal developmental gross anatomy of the proximocaudal femur, among juveniles across Canidae. From an original database of 267 independent (museum) specimens from 11 canid taxa and 1 hybrid taxon, we identified 29 ancient or modern candidate juvenile specimens (nine taxa and one hybrid taxon).

The nature of coxofemoral joint pathology across family Canidae.

We evaluated coxofemoral joints from museum specimens of: Vulpes lagopus; Vulpes vulpes; Vulpes velox; Nyctereutes procyonoides; Urocyon cinereoargenteus; Aenocyon [Canis] dirus; Canis latrans; Canis lupus lupus; Canis lupus familiaris; C. l. familiaris × latrans; and Canis dingo.

Morphology-based diagnostics of "protodogs." A commentary to Galeta et al., 2021, Anatomical Record, 304, 42-62, doi: 10.1002/ar.24500.

In a recent article in this journal, Galeta et al., (2020) discussed eight Pleistocene "protodogs" and seven Pleistocene wolves. Those "protodogs" had been diagnosed in earlier publications, based on skull morphology.

Sleep Analysis in Adult Reveals State-Dependent Alteration of Neural and Behavioral Responses.

Sleep, a state of quiescence associated with growth and restorative processes, is conserved across species. Invertebrates including the nematode exhibit sleep-like states during development, satiety, and stress. Here, we describe behavior and neural activity during sleep and awake states in adult hermaphrodites using new microfluidic methods.

A Structural Equation Model to Decipher Relationships among Water, Sanitation, and Health in -Type Unincorporated Communities.

The along the United States-Mexico border are generally self-built neighborhoods of low-income families that lack basic infrastructure. While some government assistance has provided roads and electricity, water and wastewater services are still lacking in many . This research is the first to collect a comprehensive dataset on water, sanitation, health, and living conditions in these unincorporated neighborhoods through collection of water samples and surveys; 114 households in 23 across three geographically diverse Texas counties are studied.

Designing Solute-Tailored Selectivity in Membranes: Perspectives for Water Reuse and Resource Recovery.

Treatment of nontraditional source waters (e.g., produced water, municipal and industrial wastewaters, agricultural runoff) offers exciting opportunities to expand water and energy resources via water reuse and resource recovery.

A wolf from Gravettian site Pavlov I, Czech Republic: Approach to skull pathology.

Objective: Describe pathological features on internal and external aspects of the skull of an ancient grey wolf.

Materials: Wolf remains that were found at the southwestern settlement Area A of Gravettian site Pavlov I.

Methods: Visual observation and description; microcomputed tomography; porosity and fragmentation indices for internal and external skull features; histological section of the fourth upper premolar tooth.

Seasonal contamination of well-water in flood-prone colonias and other unincorporated U.S. communities.

Many of the six million residents of unincorporated communities in the United States depend on well-water to meet their needs. One group of unincorporated communities is the colonias, located primarily in several southwestern U.S.

Water Treatment: Are Membranes the Panacea?

Alongside the rising global water demand, continued stress on current water supplies has sparked interest in using nontraditional source waters for energy, agriculture, industry, and domestic needs. Membrane technologies have emerged as one of the most promising approaches to achieve water security, but implementation of membrane processes for increasingly complex waters remains a challenge. The technical feasibility of membrane processes replacing conventional treatment of alternative water supplies (e.

The OaSiS trial: A hybrid type II, national cluster randomized trial to implement smoking cessation during CT screening for lung cancer.

Introduction: When the Centers for Medicare and Medicaid Services announced coverage for low dose CT lung cancer screening, they also mandated that imaging centers offer smoking cessation services. We designed the Optimizing Lung Screening (OaSiS) trial to evaluate strategies to implement the Public Health Service Guidelines for Treating Tobacco Use and Dependence during CT screening for lung cancer.

Methods And Design: OaSiS was implemented using a pragmatic effectiveness-implementation hybrid design in 26 imaging clinics across the United States affiliated with the National Cancer Institute's National Community Oncology Research Program (NCORP).

Osteoarthritis from evolutionary and mechanistic perspectives.

Developmental osteogenesis and the pathologies associated with tissues that normally are mineralized are active areas of research. All of the basic cell types of skeletal tissue evolved in early aquatic vertebrates. Their characteristics, transcription factors, and signaling pathways have been conserved, even as they adapted to the challenge imposed by gravity in the transition to terrestrial existence.

Features of the Femoral Proximocaudal Joint Capsule Insertion Among Canids.

This observational study was conducted to evaluate the anatomic relationship between the proximocaudal femoral joint capsule insertion and the femoral caudolateral curvilinear osteophyte (CCO), across ancient and modern domestic and non-domestic canids. Museum specimens of proximal femora were screened for presence of remnant enthesophytes of the caudal joint capsule insertion (first inclusion criterion) and then for the CCO (second inclusion criterion). The initially screened population included 267 dry bone specimens: Six Canis species, hybrid coyote × domestic dog, and five vulpines (three Vulpes species, one Urocyon, and one Nyctereutes).

A Long-Term Lens: Cumulative Impacts of Free-Roaming Cat Management Strategy and Intensity on Preventable Cat Mortalities.

This study used a previously developed stochastic simulation model (1) to estimate the impact of different management actions on free-roaming kitten and cat mortality over a 10-year period. These longer-term cumulative impacts have not been systematically examined to date. We examined seven management scenarios, including: (1) taking no action, (2) low-intensity removal, (3) high-intensity removal, (4) low-intensity episodic culling, (5) high-intensity episodic culling, (6) low-intensity trap-neuter-return (TNR), and (7) high-intensity TNR.

The Rehabilitation Enhancing Aging Through Connected Health Prehabilitation Trial.

Objective: To evaluate the proof of concept of an innovative model of physical therapy Rehabilitation Enhancing Aging through Connected Health (REACH) and evaluated its feasibility and effect on physical function and health care utilization.

Design: Quasi-experimental 12-month clinical trial.

Setting: Two outpatient rehabilitation centers.

The effect of muscle fatigue on wrist joint position sense in healthy adults.

Study Design: Pretest and posttest experimental study.

Introduction: The effect of muscle fatigue on wrist joint position sense (JPS) has yet to be determined.

Purpose Of The Study: The primary aim was to determine whether muscle fatigue affects wrist JPS in healthy adults.

Laccase removal of 2-chlorophenol and sulfamethoxazole in municipal wastewater.

Laccases were studied for their ability to remove two compounds, 2-chlorophenol and sulfamethoxazole, in batch studies, both in buffered solutions and in wastewater samples from different points in a municipal water resource recovery facility. Two enzymes with and without a mediator (acetosyringone) were investigated: a commercial product derived from Myceliphthora thermophile and a laboratory-generated enzyme mix derived from Tramates versicolor. The chlorophenol was removed rapidly by the commercial enzyme in the presence of acetosyringone, but the primary products were coupling complexes of the reactants.

Transformation kinetics of cyclophosphamide and ifosfamide by ozone and hydroxyl radicals using continuous oxidant addition reactors.

The detection of pharmaceuticals in water and wastewater has triggered human and ecological health concerns. As highly toxic compounds, chemotherapy agents (CAs), such as the cyclophosphamide (CYP) and ifosfamide (IFO) structural isomers, represent a unique threat. This research elucidated the fate of CYP and IFO during ozonation and advanced oxidation by hydroxyl radicals (HO).

Predictive Value of the Cognitive Performance Test (CPT) for Staging Function and Fitness to Drive in People With Neurocognitive Disorders.

The Cognitive Performance Test (CPT) is a standardized occupational therapy assessment that examines cognitive integration with functioning in an instrumental activities of daily living context. Conventional cognitive measures provide diagnostic utility but do not fully address the functional implications. Ninety-one veterans diagnosed with cognitive impairment were evaluated.

Effect of a Digital Health Intervention on Receipt of Colorectal Cancer Screening in Vulnerable Patients: A Randomized Controlled Trial.

Background: Screening for colorectal cancer (CRC) reduces mortality, yet more than one third of age-eligible Americans are unscreened.

Objective: To examine the effect of a digital health intervention, Mobile Patient Technology for Health-CRC (mPATH-CRC), on rates of CRC screening.

Design: Randomized clinical trial.