Publications by authors named "Lawford B"

Article Synopsis
  • Knee osteoarthritis (OA) is a significant health problem that leads to chronic pain and decreased quality of life, with exercise being a recommended self-management strategy as there is currently no cure.
  • This review evaluates the effectiveness of land-based exercise for knee OA in three ways: comparing it to control groups, to no treatment/usual care, and in combination with other interventions.
  • A total of 139 randomized controlled trials involving over 12,000 participants were analyzed, focusing on outcomes like pain relief, physical function, and quality of life, with exercise interventions ranging from 2 to 104 weeks in duration.
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Objective: Determine whether there is a relationship between the number of different lower-limb resistance exercises prescribed in a program and outcomes for people with knee osteoarthritis.

Methods: Systematic review with meta-regression. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase up to 4th January 2024.

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Article Synopsis
  • The study aimed to assess whether sticking to American College of Sports Medicine (ACSM) exercise guidelines improved exercise results for people with knee osteoarthritis (OA).
  • A systematic review analyzed various trials comparing exercise outcomes for those who followed the guidelines more closely (≥60% compliance) versus those who didn’t (<60% compliance).
  • The findings indicated no significant differences in pain and function outcomes between higher and lower compliance groups, suggesting that simply adhering to guidelines may not impact exercise benefits for knee OA patients, although results should be considered carefully due to variability and potential biases in the studies.
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Article Synopsis
  • Early- to mid-career academics (EMCAs) in Australian higher education face significant challenges that impact their wellbeing and contribute to a desire to leave academia.
  • A survey of 114 EMCAs examined their awareness of, and engagement with, diversity and inclusion initiatives, and identified a disconnect between interest in these events and actual participation.
  • Focus groups highlighted five main opportunities to improve diversity and inclusion in the workplace, including better support for career progression and reduction of structural barriers.
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Background: Accessing peer support can be difficult for people with, or carers of people with, inherited intellectual disabilities. One way to improve access is to provide services online, yet few studies have explored people's experiences with online peer support programmes. We aimed to explore experiences with such programmes for communities affected by fragile X-associated conditions.

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To explore (1) initial feelings of people with knee osteoarthritis who are unexpectedly offered telerehabilitation, and (2) if their experiences met their expectations, and their willingness to use telerehabilitation in the future. Mixed-methods study of 122 people with knee osteoarthritis who were randomized to receive physiotherapist-delivered telerehabilitation in a clinical trial. At enrollment in the trial, participants were unaware care would be delivered via telerehabilitation.

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This Year in Review presents key highlights from recent research relating to osteoarthritis rehabilitation and its outcomes, defined as any non-pharmacological and non-surgical treatment that aims to improve osteoarthritis symptoms at any joint. Three databases (Medline, Embase, and CINAHL Plus) were searched between 1 March 2023 to 12 March 2024. Relevant studies were chosen based on the predefined inclusion/exclusion criteria, perceived clinical importance, quality, controversy in the field, or personal interest, and organised into four overarching themes (with 1-5 sub-themes each).

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Objective: Explore the experiences of people with knee osteoarthritis (OA) who received a very low energy diet (VLED) and exercise program from a physiotherapist.

Methods: Mixed methods study involving questionnaires (n = 42) and semistructured interviews (n = 22) with randomized control trial participants with knee OA who had received a 6-month physiotherapist-delivered VLED weight loss and exercise intervention. Questionnaires measured participant satisfaction and perceptions about physiotherapist's skills/knowledge in delivery of the dietary intervention (measured on 5-7 point Likert scales).

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• Telehealth delivered physical therapy is effective and provides equivalent outcomes to in-person care. • Lack of telehealth knowledge is a significant barrier for implementation into clinical practice. • Physical therapy educators recognise the importance of telehealth education for emerging physical therapists.

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Background And Aims: Provision of physiotherapy services using telehealth has drastically increased since the COVID-19 pandemic and continues to be utilized in clinical practice suggesting telehealth in physiotherapy will become common practice. Prior research has explored the attitudes of physiotherapists with many years of in-person clinical experience toward telehealth. However, little is known about the emerging workforce's attitudes.

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Article Synopsis
  • PTSD genetics have been difficult to study compared to other psychiatric disorders, limiting our biological understanding of the condition.
  • A large-scale meta-analysis involving over 1.2 million individuals identified 95 genome-wide significant loci, with 80 being new discoveries related to PTSD.
  • Researchers identified 43 potential causal genes linked to neurotransmitter activity, developmental processes, synaptic function, and immune regulation, enhancing our knowledge of the neurobiological systems involved in PTSD.
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Objective: To determine the common understanding of focal muscle spasticity guidelines amongst clinicians working in spasticity clinics. To examine the facilitators and barriers to their implementation as well as their influence on clinic processes.

Design: A qualitative study based on a phenomenological approach.

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Background: Hip osteoarthritis (OA) is a leading cause of chronic pain and disability worldwide. Self-management is vital with education, exercise and weight loss core recommended treatments. However, evidence-practice gaps exist, and service models that increase patient accessibility to clinicians who can support lifestyle management are needed.

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Introduction: Quality training and mentoring are crucial components of successful career development for early mid career researchers (EMCRs). This paper describes the overarching framework of novel ongoing national Training and Mentoring Programme Melbourne University Sydney Queensland:Impact (MUSQ:Impact) for musculoskeletal researchers, including a description of how it was set up and established, and lessons learned from its implementation.

Results: The MUSQ:Impact programme spans four multidisciplinary musculoskeletal research teams across three universities in Australia, comprising 40-60 EMCR members.

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To compare the effects of diagnostic labels and their explanations on people's beliefs about managing hip pain. Online randomized controlled trial involving 626 participants. Participants aged ≥45 years with and without hip pain considered a hypothetical scenario (initial doctor consultation for hip pain).

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Article Synopsis
  • PTSD genetics are harder to study compared to other mental health disorders, resulting in limited biological insights from past research.
  • A large-scale analysis involving over 1.2 million individuals found 95 significant genetic loci related to PTSD, with 80 being new discoveries.
  • The study identified 43 potential causal genes linked to neurotransmitters, synaptic function, and immune responses, enhancing understanding of PTSD's biological mechanisms and suggesting new research directions.
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Introduction: To explore physiotherapist and patient experiences with, and acceptability of, a 12-week physiotherapist-guided combined strength and aerobic physical activity exercise programme for hip osteoarthritis (OA).

Methods: A qualitative study using semi-structured interviews with 13 people with hip OA and four physiotherapists. Patients underwent a 12-week home exercise programme customised by weekly visits with one of the four physiotherapists.

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Objective: To develop a Consumer Involvement Strategy which adheres to best practice recommendations and is feasible to implement in a small musculoskeletal research centre funded solely by external grants.

Methods: The Strategy development involved five collaborative and iterative stages: (1) conceptualisation and initial consultation; (2) formation of the Consumer Involvement Strategy Action Group; (3) defining the scope and developing the strategy; (4) consultation and refinement; and (5) presentation and implementation. The final three stages were overseen by a Consumer Involvement Strategy Action Group comprising two post-doctoral research fellows, a PhD student representative, and two consumers (people with osteoarthritis), all with experience in consumer involvement activities in research.

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Purpose Of Review: There is increasing recognition that virtual tools, enabled by the internet and telecommunications technology, can increase access to health care. We review evidence about the clinical effectiveness and acceptability of telephone-delivered and videoconferencing clinician consultations, websites and internet-delivered programs, and SMS and mobile applications in enabling the management of people with knee osteoarthritis (OA). We discuss barriers to using virtual tools and suggest strategies to facilitate implementation in clinical settings.

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Objective: To explore experiences maintaining weight loss 6 months after completing a multicomponent weight loss programme for knee osteoarthritis.

Design: Qualitative study based on an interpretivist paradigm and a phenomenological approach that was embedded within a randomised controlled trial.

Setting: Semistructured interviews were conducted with participants 6 months after completing a 6-month weight loss programme (ACTRN12618000930280) involving a ketogenic very low calorie diet (VLCD), exercise and physical activity programme, videoconferencing consultations with a dietitian and physiotherapist, and provision of educational and behaviour change resources and meal replacement products.

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Objective: To explore the mediators of effects of two 6-month telehealth-delivered exercise programs, including exercise with and without weight-loss diet, on pain and function improvements in knee osteoarthritis (OA).

Methods: Secondary analysis of 345 participants from a 3-arm randomized controlled trial of exercise (Exercise program) and exercise plus diet (Diet + Exercise program) versus information (Control program) was conducted. Outcomes were changes in pain (11-point numeric rating scale) and function (Western Ontario and McMaster Universities Osteoarthritis Index [score range 0-68]) at 12 months.

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Background: Early- and mid-career academics in medicine, dentistry and health sciences are integral to research, education and advancement of clinical professions, yet experience significant illbeing, high attrition and limited advancement opportunities.

Objectives: Identify and synthesise published research investigating challenges and opportunities related to diversity and inclusion, as experienced by early and mid-career academics employed in medicine, dentistry and health sciences disciplines.

Design: Rapid review.

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Article Synopsis
  • The study aimed to create a toolkit to enhance exercise delivery for individuals with hip or knee osteoarthritis by identifying key components and practical resources.
  • An international survey involving clinicians, patients, and researchers collected input on what practical resources are necessary for effective exercise implementation, resulting in 551 responses analyzed into 72 unique insights.
  • The findings highlighted nine key domains for resource development, including accessibility, quality, customization for individuals, and support mechanisms, laying the groundwork for a toolkit that aligns with global exercise guidelines.
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Objective: Accurate knowledge is central to effective self-care of osteoarthritis (OA). This study aimed to assess the measurement properties of the Osteoarthritis Knowledge Scale (OAKS) with versions for the hip and knee.

Methods: Participants with hip OA (n = 144), knee OA (n = 327), and no OA (n = 735) were recruited.

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Background: To explore attitudes to telehealth education and experiences incorporating telehealth education into entry-to-practice physiotherapy programs in Australia, from the perspective of university educators.

Methods: Qualitative design based on a constructivist paradigm and a phenomenological approach. Sixteen university educators (who had a responsibility for telehealth curriculum or oversight of the broader curriculum in an entry-to-practice physiotherapy programme at an Australian university) were recruited.

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