Publications by authors named "Lavu Rohit Reddy"
Exp Hematol Oncol
July 2023
Article Synopsis
- * Key factors contributing to MDS/AML include variations in Toll-like receptors (TLRs), abnormal MyD88 levels, and disruptions in signaling pathways like NF-κβ and TGF-β.
- * The review highlights recent clinical trials exploring new treatments targeting these immune pathways, including monoclonal antibodies and small molecule inhibitors.
Ecancermedicalscience
May 2023
Article Synopsis
- Li Fraumeni syndrome (LFS) is a hereditary cancer risk condition linked to TP53 mutations, with limited research on its impact in the Indian population.
- A study of nine families revealed 29 patients with various cancers, with a notable percentage diagnosed before age 18, underscoring significant childhood cancer risk.
- The study found common cancers like sarcomas and breast cancer, with multiple familial cases, highlighting the importance of genetic testing and early surveillance to catch asymptomatic carriers before cancer develops.
