The data, concerning significance of indices, characterizing trophic peculiarities of the patients, were presented, basing on comparative analysis of two groups of these persons, in whom restrictive (in 41) and shunting (in 32) bariatric interventions were done for obesity. Conclusion, concerning comparable efficacy of both procedures and prognostic significance of the body mass index loss, was made.
View Article and Find Full Text PDFThe influence of a low-molecular fraction (below 5 kDa) from the cattle cord blood (CBF) on functional activity of phagocytes, human embryonic fibroblasts, mesenchymal stromal cells and BHK-21 clone 13/04 and PK-15 cells was studied. The low-molecular fraction added to culture medium increases the growth rate of cell cultures. The incubation of leukoconcentrate in the CBF-containing medium results in an increase in phagocytic indices ofneutrophils in the presence of a phagocytosis inhibitor--sodium iodoacetate, leading to a significant increase in intracellular glucose content and alkaline phosphatase activity as compared to the control and the reference drug Actovegin®.
View Article and Find Full Text PDFThe capacities of the cattle cord blood low-molecular fraction (below 5 kDa) and Actovegin (the vealer blood fraction (below 5 kDa)) for recovering functions of cell cultures after cryopreservation compared. Their influence proliferation of the flozen-thawed cell cultures, certain stages of their growth, cell attachment, rate of cell spreading, and mitotic regiment has been studied. Both the cord blood low-molecular fraction and Actovegin were shown to stimulate growth of the cell cultures after cryopreservation more efficiently at the concentration of 224 μg/ml.
View Article and Find Full Text PDFThe influence of the cattle cord blood fraction with molecular weight of components below 5 kDa on adhesive and proliferative properties of continuous cell lines BHK-21 clone q3/04 and PK-15-IECVM was investigated in comparison with the preparation "Actovegin". It was shown that adding this fraction as well as "Actovegin" to growth media did not affect the efficiency of culture attachment, promoted culture spreading, improved cell morphology and stimulated mitotic activity of the cultures. The efficiency of the cord blood fraction below 5 kDa estimated by the induces studied was found to be higher than the "Actovegin" efficiency when cells being cultivated in the media different contents of blood serum.
View Article and Find Full Text PDFThe influence of Actovegin on proliferation activity and mitotic regimen of cells of permanent lines PK-15-IEKVM and BHK-21 clone 13/04 was investigated. Addition of Actovegin into growth media containing bovine serums of different components and concentrations stimulates cell proliferation. Conclusion has been made that Actovegin can be used in cell culture biotechnology.
View Article and Find Full Text PDFThe efficacy of prophylaxis of tromboembolic complications in surgical treatment of 331 patients with morbid obesity, who underwent different bariatric operations, is estimated. The comparative analysis and results of application of non-fractionized heparin and low molecular weight heparins (Fraxiparin) in patients, suffering morbid obesity, are presented.
View Article and Find Full Text PDFGastric shunting constitutes standard bariatric intervention in USA and Western Europe countries. In the states of Eastern Europe and CIS these operations are still introducing. Technique of modern modifications of gastric shunting is depicted, own results of its application in 37 patients, suffering morbid obesity, are presented.
View Article and Find Full Text PDFGastric shunting (GS) constitutes one of the most effective surgical methods of treatment of morbid obesity. In USA and European countries GS constitutes standard bariatric intervention, in Ukraine these operations were not performed before. The technique of the most popular GS operations was depicted, own results of their application were presented.
View Article and Find Full Text PDFThe first experience of extramucosal laparoscopic esophagocardiomyotomy performance in 12 patients for achalasia of cardia was summarized. There were presented main technical stages of the operation, indications, early and immediate results of its application as well.
View Article and Find Full Text PDFExperience of surgical treatment of 8 patients with morbid obesity, using regulated cuff Lap Band, was adduced. Body mass of patients have constituted from 105 to 185, (14.5 +/- 2.
View Article and Find Full Text PDFThe results of comparative clinical application of low-molecular heparin Clexan vs heparin for the thromboembolic complications prophylaxis in surgical treatment of morbid obesity were summarized.
View Article and Find Full Text PDFExperience of the reoperations performance after jejunoileoshunting and gastric volume reducing operations for morbid obesity (MO) was demonstrated on. They may serve as a concluding phase of MO surgical treatment (various variants of dermatolipectomy) or as a reconstructive-restorational operations, directed on correction of various pathological syndromes.
View Article and Find Full Text PDFThe results of the gastric morphofunctional state after the gastric banding operation performance were analysed. In the late follow-up period after the operation there were not noted the severe gastric changes as well as its function disorder.
View Article and Find Full Text PDFVertical gastroplasty was applied in surgical treatment of obesity in two patients. There were no complications. During the first year after the operation the patients body mass have reduced by 35-41 kg (25-29% of initial).
View Article and Find Full Text PDF