Remote immune processes revealed by immune-derived circulating cell-free DNA.

Blood cell counts often fail to report on immune processes occurring in remote tissues. Here, we use immune cell type-specific methylation patterns in circulating cell-free DNA (cfDNA) for studying human immune cell dynamics. We characterized cfDNA released from specific immune cell types in healthy individuals (N = 242), cross sectionally and longitudinally.

Impairments of interpersonal synchrony evident in attention deficit hyperactivity disorder (ADHD).

In addition to well-known attention deficiencies, attention deficit hyperactivity disorder (ADHD) is accompanied by deficiencies in social cognition. Both intentional and spontaneous interpersonal synchrony have been found to be an essential part of successful human interaction. Here, we used a novel paradigm to assess intentional and spontaneous interpersonal synchrony in adults with and without ADHD.

Influence of Vinyl Polysiloxane Impression Techniques on Marginal Fit of Metal Frameworks for Fixed Partial Dentures.

Impression technique is one of the factors affecting restoration fit accuracy, which is a major aspect influencing its survival. The purpose of this study is to compare, in vivo, the effect of two commonly used Vinyl Polysiloxane (VPS) impression techniques on the metal framework fitting of fixed partial dentures. Ninety-two consecutive patients, diagnosed as partially edentulous, treated by fixed partial denture restorations, participated in the study.

Bilateral symmetry of anterior maxillary incisors: evaluation of a community-based population.

The final outcome of dental treatment needs to be not only clinically sufficient, but also esthetically pleasing. Bilateral symmetry in the maxillary incisor teeth is of significant importance in esthetic dentistry. In restorative dentistry, symmetry refers to the appearance of balance around the dental midline.

Bone microstrain values of 1-piece and 2-piece implants subjected to mechanical loading.

Purpose: The purpose of this study was to measure and compare the strain levels in peri-implant bone as generated by 1-piece (1P) and 2-piece (2P) implant systems.

Materials And Methods: The implants (1P and 2P) were placed into bovine bone according to the manufacturer's protocol. Four linear strain gauges were placed around each implant neck and apex.

Retrospective clinical evaluation of tapered implants: 10-year follow-up of delayed and immediate placement of maxillary implants.

Objectives: To retrospectively evaluate the clinical outcome of tapered, multithreaded implants (Tapered Screw-Vent MTX; Zimmer Dental, Inc, Carlsbad, CA) with an emphasis on periimplant crestal bone status around those placed delayed and immediately in the posterior and anterior maxilla.

Methods: Chart reviews were performed on 46 patients who had been treated with 173 implants replacing one or more missing and/or unsalvageable teeth in the maxilla. Implant placement and loading was either immediate or delayed.

The effect of high versus low loading on bone strength in middle life.

While bone mass and geometry are largely genetically determined, mechanical loading is considered to be an important additional determinant. This study investigates to what extent very high mechanical loading begun at a young age and sustained afterward can affect tibia bone mass and geometry in middle age. Cohorts from a common ethnic background, with a history of very high and very low tibia bone loading based on an assessment of their activities according their strain levels were compared.

Fatal voluntary salt intake resulting in the highest ever documented sodium plasma level in adults (255 mmol L-1): a disorder linked to female gender and psychiatric disorders.

Excessive ingestion of salt is a well-recognized cause of hypernatraemia in children, is uncommonly recognized in debilitated elderly persons, but is rarely diagnosed in healthy, independent adults. We report a case of fatal salt poisoning in a 20-year-old lady who suffered of post-natal depression and ingested large quantities of salt as part of exorcism ritual. She presented with the highest ever documented serum sodium level of 255 mmol L(-1), associated with severe neurological impairment that was unresponsive to aggressive hypotonic fluid replacement.

Group G streptococcal bacteremia in Jerusalem.

Group G Streptococcus (GGS) can cause severe infections, including bacteremia. These organisms often express a surface protein homologous to the Streptococcus pyogenes M protein. We retrospectively studied the characteristics of patients from the Hadassah Medical Center with GGS bacteremia from 1989 to 2000.