Publications by authors named "Laurione C de Oliveira"
Prevalence of Testicular Adrenal Rest Tumor and Factors Associated with Its Development in Congenital Adrenal Hyperplasia.
Horm Res Paediatr
February 2019
Background: Testicular adrenal rest tumors (TART) can cause infertility in congenital adrenal hyperplasia (CAH) males.
Aims: To determine TART prevalence in patients with CAH due to 21-hydroxylase deficiency (21-OHD) and evaluate possible factors associated with its development.
Methods: This is a descriptive and analytical cross-sectional study evaluating males with the classical form of 21-OHD through testicular ultrasonography and serum inhibin B dosages.
Comparison between two inhibin B ELISA assays in 46,XY testicular disorders of sex development (DSD) with normal testosterone secretion.
J Pediatr Endocrinol Metab
January 2018
Article Synopsis
- * The study examined serum inhibin B levels in 29 patients diagnosed with various forms of 46,XY DSD using two different ELISA assays (Beckman-Coulter and AnshLabs).*
- The results showed a high interclass correlation (0.915), but significant discrepancies between the assays suggest that the same kit should be used for consistent measurements in patients.*
Article Synopsis
- This study analyzed 408 cases of disorders of sex development (DSD) with ambiguous genitalia over a 23-year period, focusing on diagnosis, age of referral, karyotype, and sex of rearing.
- The majority of cases were 46,XY (61.3%), with common conditions including testicular DSD and ovarian DSD, while congenital adrenal hyperplasia was the leading cause.
- The average age for diagnosis was 31.7 months, with a final sex of rearing predominantly male (238 cases) and only a small percentage (6.6%) requiring sex reassignment.
Purpose: Positive impact of weight loss on sexual function and hormones has been demonstrated, and male fertility in this scenario is to be better defined. We evaluated the impact of lifestyle modifications and gastric bypass on sperm quality.
Methods: We prospectively studied 20 morbidly obese men during 24 months, randomized for intervention: lifestyle modifications (exercise and diet) for 4 months and subsequently gastric bypass (n = 10); and control: follow-up (n = 10).
Purpose: The presence of neuroendocrine differentiation may play a key role in androgen-independent tumor progression. The prognostic significance of plasma chromogranin-A (CgA) was assessed in a series of consecutive patients with high-risk prostate cancer (PCa).
Patients And Methods: Twenty-three patients presenting high-risk PCa and 8 healthy individuals, as control group, had their blood samples collected to evaluate CgA, free and total prostate specific antigen, and free and total testosterone in a pilot study.
Aim: To analyze the changes in IGF-1, IGFBP-3, leptin and insulin after replacement doses of recombinant human growth hormone (rhGH) in short prepubertal children with chronic renal failure (CRF).
Patients And Methods: Eleven children (3F:8M), with mean age of 9.6 years, were treated with rhGH (0.