Ischemic stroke risk factors not included in the CHADS-VASC score in patients with non-valvular atrial fibrillation.

Background: In patients with atrial fibrillation, the CHADS-VAS score guides stroke prevention using anticoagulants, but it is an imperfect score. Other potential risk factors such as renal failure, the type of atrial fibrillation, active smoking, cancer, sleep apnea or systemic inflammation have less well been investigated.

Objective: To assess the impact of these factors on ischemic stroke risk in patients with non-valvular atrial fibrillation.