Sarcocystosis, presumably caused by , was diagnosed in 2 purpose-bred, SPF Dutch belted laboratory rabbits from a class A breeder. The rabbits were purchased by a research facility and conventionally housed individually in stainless-steel suspended caging. At necropsy and tissue harvest, gross lesions were not observed in the muscles.
View Article and Find Full Text PDFThe gut microbiome plays an important role in the health of dogs. Both beneficial microbes and overall diversity can be modulated by diet. Fermentable sources of fiber in particular often increase the abundance of beneficial microbes.
View Article and Find Full Text PDFThe efficacy of brushing the teeth of beagle dogs in a randomized, controlled, blinded study design using a clearly-defined brushing technique was evaluated for 4 brushing frequencies: brushing daily, brushing every other day, brushing weekly and brushing every other week, compared with no brushing in a control group of dogs. All dogs were fed a standard dry kibble diet during the study. Standard plaque, calculus, and gingivitis indices were used to score the teeth.
View Article and Find Full Text PDFObjective: To document clinicopathologic, histologic, and toxicologic findings in cats inadvertently exposed to pet food contaminated with melamine and cyanuric acid.
Design: Case series.
Animals: 70 cats from a single cattery inadvertently fed contaminated food that was the subject of a March 2007 recall.
Evaluation of a pharmaceutical's safety includes assessment of the potential for ophthalmologic toxicity. These nonclinical studies commonly use various outbred stocks of mice. Pretest indirect ophthalmoscopic examinations in the commonly used outbred stock Hsd:ICR(CD-1) indicated that retinal degeneration was a problem in this particular outbred stock of mice.
View Article and Find Full Text PDFReference values for serum clinical chemistry and hematology parameters are often sought after when attempting to interpret clinical pathology data. Furthermore, the values of parameters may vary between laboratories depending on the techniques being used. Accordingly, laboratories should strive to generate a historical reference value database based upon the methods used.
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