The Rising Incidence of Hyperinsulinemic Hypoglycemia: Connection With Maternal Health.

Objective: Due to a perceived rise in hyperinsulinemic hypoglycemia (HH) cases over time, notably during the COVID-19 pandemic, institutional experiences between 2013 and 2021 were reviewed to evaluate trends, characteristics, and outcomes in children with HH.

Methods: Charts of all children diagnosed with HH during the study period and evaluated by Pediatric Endocrinology were reviewed. HH was defined per Pediatric Endocrine Society guidelines.

An E-Textile Respiration Sensing System for NICU Monitoring: Design and Validation.

The world is witnessing a rising number of preterm infants who are at significant risk of medical conditions. These infants require continuous care in Neonatal Intensive Care Units (NICU). Medical parameters are continuously monitored in premature infants in the NICU using a set of wired, sticky electrodes attached to the body.

Enhancing the NICU language environment with a neonatal Cuddler program.

Objective: To compare effects of a language intervention on Cuddler and parent adult word counts (AWC), and to compare Cuddler versus parent and nurse-care times.

Design: Prospective pilot cohort intervention study. Twelve Cuddler-low-visit (≤2/week) infant pairs and 17 high-visit (≥3/week) parent-infant pairs were enrolled.

Randomised control language intervention for infants of adolescent mothers.

Aim: Create a Language ENvironment Analysis (LENA)-based intervention to increase adolescent and infant speech and improve 12-month language outcomes.

Methods: Randomised control trial of adolescent (15-19 years) mother-infant pairs comparing language-motor (intervention) and motor (control) groups. Intervention included reviewing language-motor curriculums, formative feedback on 4 LENA recordings (baseline, post-curriculum, 4 and 12-months) and 16-weekly language-motor texts.

Neonatal oesophageal and axilla temperatures in the neonatal intensive care unit care.

Aim: To compare oesophageal and axilla temperatures in routine neonatal intensive care unit (NICU) care.

Methods: Prospective observational study of NICU infants with indwelling oral/nasogastric tubes. Three simultaneous temperature measurements were taken: Physitemp axilla, digital Premie Faichney axilla in predictive mode and Physitemp oesophageal.

Developmental outcomes of extremely preterm infants born to adolescent mothers.

Background And Objectives: Extremely preterm infants and infants born to adolescent mothers are at risk for adverse developmental. The objectives were to evaluate development and behavior outcomes of extremely low birth weight (ELBW) infants born to adolescent mothers <20 compared with adult mothers ≥20 years and to identify socioeconomic risk factors that affect outcomes.

Methods: Retrospective cohort analysis of 211 infants >27 weeks of adolescent mothers and 1723 infants of adult mothers at Neonatal Research Network centers from 2008 to 2011.

Extensive placental choriovascular infiltration by maturing myeloid cells in down syndrome-associated transient abnormal myelopoiesis.

Transient abnormal myelopoiesis (TAM), a clonal proliferation of predominantly megakaryocytic precursor cells, affects 4%-10% of newborns with Down syndrome. Approximately 20%-30% of TAM survivors are at risk of development of acute myeloid leukemia (myeloid leukemia associated with Down syndrome, ML-DS). We report unusual placental findings in a female infant with trisomy 21 born at 38 weeks of gestation.

Physiological and behavioral evidence for focal nociception induced by epidural glutamate infusion in rats.

Study Design: Blinded animal study.

Objectives: To determine if an increased concentration of epidural glutamate can cause a focal nociceptive response in the lower extremities that is consistent with sciatica.

Summary Of Background Data: It is believed that the origin of sciatic pain is related to more than physical pressure on the nerve roots.