Behav Brain Sci
October 2023
Technological innovations for online communication reduce the impact of signal transience on meaning standardization while boosting access to reliable patterning across multiple linguistic and nonlinguistic contexts - both asynchronous and synchronous. We classify emojis as ideographic symbols, examine their interdependence with surrounding words when reading/writing, and argue that emoji use validates the potential for meaning standardization in ideographs.
View Article and Find Full Text PDFEmojis have many functions that support reading. Most obviously, they convey semantic information and support reading comprehension (Lo, CyberPsychology & Behavior, 11[5], 595-597, 2008; Riordan, Computers in Human Behavior, 76, 75-86, 2017b). However, it is undetermined whether emojis recruit the same perceptual and cognitive processes for identification and integration during reading as do words.
View Article and Find Full Text PDFWe describe the evolution of a stereotype as it emerged in tweets about the Charlie Hebdo terrorist attack in Paris in early 2015. Our focus is on terms associated with the Muslim community and the Islamic world. The data (400k tweets) were collected via Twitter streaming API and consisted of tweets that contained at least one of 16 hashtags associated with the Charlie Hebdo attack (e.
View Article and Find Full Text PDFIn our commentary on Branigan & Pickering (B&P), we start by arguing that the authors implicitly adopt several assumptions, the consequence of which is to make further claims necessary and/or sufficient. Crucially, the authors assume the existence of discrete units at various levels of linguistic granularity that then must be operated upon by combinatorial mechanisms and rules (i.e.
View Article and Find Full Text PDFWe draw parallels between emoticons in textual communication and gesture in signed language with respect to the interdependence of codes by describing two contexts under which the behavior of emoticons in textual communication resembles that of gesture in speech. Generalizing from those findings, we propose that gesture is likely characterized by a nuanced interdependence with language whether signed, spoken or texted.
View Article and Find Full Text PDFIn this study we present a novel set of discrimination-based indicators of language processing derived from Naive Discriminative Learning (ndl) theory. We compare the effectiveness of these new measures with classical lexical-distributional measures-in particular, frequency counts and form similarity measures-to predict lexical decision latencies when a complete morphological segmentation of masked primes is or is not possible. Data derive from a re-analysis of a large subset of decision latencies from the English Lexicon Project, as well as from the results of two new masked priming studies.
View Article and Find Full Text PDFThe main question that Firestone & Scholl (F&S) pose is whether "what and how we see is functionally independent from what and how we think, know, desire, act, and so forth" (sect. 2, para. 1).
View Article and Find Full Text PDFMany models of word recognition assume that processing proceeds sequentially from analysis of form to analysis of meaning. In the context of morphological processing, this implies that morphemes are processed as units of form prior to any influence of their meanings. Some interpret the apparent absence of differences in recognition latencies to targets (SNEAK) in form and semantically similar (sneaky-SNEAK) and in form similar and semantically dissimilar (sneaker-SNEAK) prime contexts at a stimulus onset asynchrony (SOA) of 48 ms as consistent with this claim.
View Article and Find Full Text PDFIn the present study, we demonstrate that ectopic expression of 56-kDa human selenium binding protein-1 (hSP56) in PC-3 cells that do not normally express hSP56 results in a marked inhibition of cell growth in vitro and in vivo. Down-regulation of hSP56 in LNCaP cells that normally express hSP56 results in enhanced anchorage-independent growth. PC-3 cells expressing hSP56 exhibit a significant reduction of hypoxia inducible protein (HIF)-1α protein levels under hypoxic conditions without altering HIF-1α mRNA (HIF1A) levels.
View Article and Find Full Text PDFComparisons across languages have long been a means to investigate universal properties of the cognitive system. Although differences between languages may be salient, it is the underlying similarities that have advanced our understanding of language processing. Frost is not unique in emphasizing that the interaction among linguistic codes reinforces the inadequacy of constructing a model of word recognition where orthographic processes operate in isolation.
View Article and Find Full Text PDFSemantically similar (e.g., coolant-COOL) primes have produced greater facilitation than have form-similar but semantically dissimilar (e.
View Article and Find Full Text PDFThe authors compared performance on two variants of the primed lexical decision task to investigate morphological processing in native and non-native speakers of English. They examined patterns of facilitation on present tense targets. Primes were regular (billed-bill) past tense formations and two types of irregular past tense forms that varied on preservation of target length (fell-fall; taught-teach).
View Article and Find Full Text PDFWords can be similar with respect to form (viz., spelling, pronunciation), meaning, or both form and meaning. In three lexical decision experiments (48 ms forward masked, 116 ms, and 250 ms SOAs), targets (e.
View Article and Find Full Text PDFRecombinant human erythropoietin (rhEPO) has been used clinically to alleviate cancer- and chemotherapy-related anemia. However, recent clinical trials have reported that rhEPO also may adversely impact disease progression and survival. The expression of functional EPO receptors (EPOR) has been demonstrated in many human cancer cells where, at least in vitro, rhEPO can stimulate cell growth and survival and may induce resistance to selected therapies.
View Article and Find Full Text PDFMany studies have suggested that a word's orthographic form must be processed before its meaning becomes available. Some interpret the (null) finding of equal facilitation after semantically transparent and opaque morphologically related primes in early stages of morphological processing as consistent with this view. Recent literature suggests that morphological facilitation tends to be greater after transparent than after opaque primes, however.
View Article and Find Full Text PDFErythropoietin receptors have been identified on a variety of cancer-derived cell lines and primary cancer cells, including those of prostate cancer. The functional status of these extrahematopoietic erythropoietin receptors remains a matter of some dispute. The publication of several important clinical trials suggesting a direct effect of erythropoietin on the growth and survival of primary tumors adds further importance to the question of whether erythropoietin receptors on cancer cells are functional.
View Article and Find Full Text PDFThe authors examined patterns of facilitation under forward-masked priming conditions across 3 list contexts (Experiments 1-3) that varied with respect to properties of filler trials -- (a) mixed (morphological, orthographic, semantic), (b) identity, and (c) semantic -- but held the relatedness proportion constant (75%). Facilitation for targets that were related morphologically to their prime occurred regardless of filler context, but facilitation for semantically related pairs occurred only in the context of identity and semantic fillers. Facilitation was absent for orthographically similar prime-target pairs in all 3 filler contexts when matching numbers of orthographically similar word-word and word-nonword prime-target pairs rendered orthographic similarity uninformative with respect to lexicality of the target.
View Article and Find Full Text PDFErythropoietin (Epo), a glycoprotein hormone that is the principal regulator of erythropoiesis, is known to act also on nonhematopoietic cell types. Epo receptors have been reported on several normal and neoplastic human cells and tissues, including ovarian cancer cells. We found that long-term Epo treatment of A2780 cells resulted in the development of a phenotype exhibiting both enhanced Epo signaling, evidenced by increased peak levels of phospho-Erk1/2 and increased paclitaxel resistance.
View Article and Find Full Text PDFWe used a cross-modal priming procedure to explore the processing of irregular and regular English verb forms in both monolinguals and bilinguals (Serbian-English, Chinese-English). Materials included irregular nested stem (drawn-DRAW), irregular change stem (ran-RUN), and regular past tense-present tense verb pairs that were either low (guided-GUIDE) or high (pushed-PUSH) in resonance, a measure of semantic richness. Overall, semantic richness of irregular verbs (nested and irregular change) and of regular verbs (high and low resonance) was matched.
View Article and Find Full Text PDFLabeling of recombinant proteins with polypeptide fusion partners, or affinity tagging, is a useful method to facilitate subsequent protein purification and detection. Poly-histidine tags (His-tags) are among the most commonly used affinity tags. We report strikingly variable immunodetection of two His-tagged recombinant human erythropoietins (Epo): wild type Epo (Epo(wt)) and Epo containing an R103A mutation (Epo(R103A)).
View Article and Find Full Text PDFBackground: Erythropoietin (Epo), the principal regulator of erythroid progenitor survival, growth, and differentiation, initiates its action by binding to its cognate cell surface receptor (EpoR). EpoR have been identified on a variety of non-hematopoietic cells, both normal and malignant, however, little is known about the function of EpoR on malignant cells.
Methods: RT-PCR, Western blotting, and immunohistochemistry were used to demonstrate that prostate cancer cells express EpoR at both the gene and protein level.
Linguists distinguish between words formed from free stems (e.g., actor: act) and those formed from bound stems (e.
View Article and Find Full Text PDFWe examined the influence of semantic transparency on morphological facilitation in English in three lexical decision experiments. Decision latencies to visual targets (e.g.
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