Correction: Barthélémy et al. Direct Comparative Analysis of a Pharmacogenomics Panel with PacBio Hifi Long-Read and Illumina Short-Read Sequencing. 2023, , 1655.

In the original publication [...

Direct Comparative Analysis of a Pharmacogenomics Panel with PacBio Hifi Long-Read and Illumina Short-Read Sequencing.

Background: Pharmacogenetics (PGx) aims to determine genetic signatures that can be used in clinical settings to individualize treatment for each patient, including anti-cancer drugs, anti-psychotics, and painkillers. Taken together, a better understanding of the impacts of genetic variants on the corresponding protein function or expression permits the prediction of the pharmacological response: responders, non-responders, and those with adverse drug reactions (ADRs).

Objective: This work provides a comparison between innovative long-read sequencing (LRS) and short-read sequencing (SRS) techniques.