Publications by authors named "Laurie D Labree"
Objective: To identify factors associated with variability in retinal nerve fiber layer (RNFL) thickness measurements obtained by optical coherence tomography (OCT).
Design: Retrospective observational case series.
Participants: One hundred fifty consecutive patients with known or suspected glaucomatous optic nerve damage undergoing OCT imaging for RNFL thickness measurement.
Purpose: To evaluate the use of intravitreal triamcinolone (IVTA) for the treatment of macular edema secondary to immune recovery uveitis (IRU) in patients with AIDS.
Design: Prospective, consecutive, interventional case series.
Participants: Eight eyes of 7 patients receiving 13 injections.
Purpose: To determine if multifocal electroretinogram (mfERG) testing shows abnormalities that correspond to perimetric defects in HIV positive patients without infectious retinitis.
Methods: We studied three groups of patients: HIV negative controls, HIV high CD4 nadir patients (lowest CD4 T cell count is over 100) and low CD4 nadir patients (below 100 for over 6 months). Twenty-six HIV positive eyes and 16 HIV negative control eyes were studied by mfERG.
Purpose: To investigate the effect of esterified estrogens combined with methyltestosterone (EECM) (Estratest, Solvay, Pharmaceuticals, Inc, Baudette, Minnesota, USA) on intraocular pressure (IOP) in postmenopausal women.
Design: Observational case series.
Methods: The IOP of 13 consecutive postmenopausal women with dry eye syndrome were recorded before and during EECM therapy (1.
Article Synopsis
- The study assessed the effects of an octapeptide called A 6 on reducing choroidal neovascularization (CNV) induced by laser in monkeys.
- Twenty female cynomolgus monkeys were divided into groups receiving either weekly or monthly A 6 injections, and their CNV levels were monitored over four weeks.
- Results showed that monthly injections led to a significant 71% reduction in CNV compared to controls, while weekly injections saw a smaller 35% reduction; both methods showed no signs of toxicity, indicating A 6's potential for treating similar conditions in humans.
Objective: To report the frequency and severity of optical coherence tomography (OCT) retinal thickness measurement errors and to describe parameters that predict these errors.
Design: Observational case series.
Participants: Two hundred consecutive patients undergoing OCT imaging.
Purpose: To evaluate the percentage and risk indicators leading to retinal redetachment in HIV (human immunodeficiency virus) patients with CMV (cytomegalovirus) retinitis related retinal detachments that were repaired with silicone oil, and then subsequently underwent oil removal.
Design: Retrospective, noncomparative interventional case series.
Methods: The study cohort consisted of a series of 15 eyes in 14 patients with HIV and CMV retinitis with a retinal detachment (RD) repaired with silicone oil at a single center and followed from the time of the CMV retinitis diagnosis through the time of silicone oil removal.