Passive Expiration From Total Lung Capacity Can Estimate Expiratory Function in Infants A Retrospective Study.

Background: Evaluating expiratory airway function in infants is challenging because the criterion standard, the raised-volume rapid thoracoabdominal compression technique, is technically difficult and has a high failure rate.

Research Question: Are measurements obtained during passive expiration from total lung capacity correlated with forced expiration measurements obtained by the raised-volume technique in infants?

Study Design And Methods: This observational retrospective analysis included infants born ≥ 36 weeks' gestation who underwent pulmonary function testing using the raised-volume rapid thoracoabdominal compression technique at Hadassah Medical Centre between January 2011 and December 2019. Technically acceptable forced and passive flow-volume curve measurements were included in the analysis.

Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age.

Background: Preterm infants suffer from significant respiratory morbidity during the first years of life, but the underlying lung pathophysiology is not fully understood. This study aimed to comprehensively characterize the pulmonary functions of preterm infants using full infant pulmonary function testing (iPFT).

Methods: Between 2008 and 2019, we recruited 150 infants (M 10.

The Abbreviated Methacholine Challenge Test is Safe for Children.

Objective: To evaluate the safety of an abbreviated methacholine challenge test (MCT) protocol in children.

Study Design: This prospective, observational study enrolled children aged 6 through 18 years referred for the MCT. The abbreviated protocol was initiated with a methacholine dose of 0.

Infant pulmonary function tests in individuals with Down syndrome.

Background And Objective: Down syndrome is associated with significant respiratory morbidity. The available pulmonary function testing data in school aged children and adults with Down show evidence of restrictive lung disease. We aimed to evaluated infant pulmonary function tests (iPFTs) in individuals with Down.