Publications by authors named "Laurianne R Garabed"
Article Synopsis
- This article reviews recent advances in understanding, diagnosing, and treating nonobstructive azoospermia, a condition that causes male infertility due to lack of sperm production.
- Key findings highlight the investigation of cellular dysfunction in both somatic and germ cells, as well as the potential of using cell-free DNA and RNA as biomarkers for predicting sperm retrieval success.
- Innovative technologies, including microfluidics, machine learning for sperm identification, and 3D culture techniques for sperm regeneration, are paving the way for breakthroughs in male reproductive health.
Some medications used to treat comorbidities and conditions in reproductive-aged individuals could have a negative impact on fertility. This may occur through hormonal disruption, toxicity to germ cells and spermatozoa, functional impact on the sperm, teratogenicity potential, or ejaculatory abnormalities. Having knowledge of these potential interactions between medications and reproductive potential is important for clinicians to be aware of and guide the patient, along with their treating clinicians, to reproductively favorable alternatives when available.
View Article and Find Full Text PDFPurpose: Neutrophil-to-lymphocyte ratio (NLR), a marker for subclinical inflammation, has been previously shown to be associated with erectile dysfunction (ED). We studied the potential predictive value of the NLR on ED after prostate brachytherapy (PB) for PCa.
Methods And Materials: Between July 2005 and January 2021, 842 patients were included in this retrospective study of a prospectively maintained database.
Introduction: We aimed to compare objective structured clinical examinations (OSCE) performance of residents from four Canadian urology programs, based on resident and station characteristics. We also aimed to evaluate OSCE contents by station type and subspecialty.
Methods: Scores of 109 postgraduate year (PGY)-3 to PGY-5 residents were retrospectively reviewed from 19 OSCEs from May 2008 to February 2019.
α-Synuclein is a key player in the pathogenesis of Parkinson disease (PD). Expression of human heme oxygenase-1 (HO-1) in astrocytes of GFAP.HMOX1 transgenic (TG) mice between 8.
View Article and Find Full Text PDF