A Randomized Pilot Trial of the Donor Conception Tool to Empower Parental Telling and Talking (TELL Tool) with Their Children About Their Genetic Origins.

Introduction: Parents who use donated gametes or embryos to form their families struggle with telling their children about their genetic origins. We developed the Tool to Empower Parental Telling and Talking (TELL Tool) to support parents in disclosure to their children and an eBook attention control.

Method: A randomized parallel, two-group, attention-controlled clinical pilot trial was conducted online during COVID-19.

Metabolic and endocrine status associate with obstructive sleep apnea risk among patients with polycystic ovary syndrome.

Study Objectives: Risk of obstructive sleep apnea (OSA) appears to be increased among patients with polycystic ovary syndrome (PCOS), but the underlying physiology is unclear. We sought to identify predictors of OSA risk among patients with PCOS.

Methods: A cross-sectional analysis of patients evaluated for PCOS at a single tertiary center from 2017-2022 was completed.

Development of the Tool to Empower Parental Telling and Talking (TELL Tool): A digital decision aid intervention about children's origins from donated gametes or embryos.

Objective: This study aimed to create and develop a well-designed, theoretically driven, evidence-based, digital, decision Tool to Empower Parental Telling and Talking (TELL Tool) prototype.

Methods: This developmental study used an inclusive, systematic, and iterative process to formulate a prototype TELL Tool: the first digital decision aid for parents who have children 1 to 16 years of age and used donated gametes or embryos to establish their families. Recommendations from the International Patient Decision Aids Standards Collaboration and from experts in decision aid development, digital health interventions, design thinking, and instructional design guided the process.

Decision regret among women considering planned oocyte cryopreservation: a prospective cohort study.

Purpose: To (1) prospectively characterize the incidence of decision regret among women considering planned oocyte cryopreservation (planned OC), comparing those who pursued treatment vs those who did not freeze eggs, and (2) to identify baseline predictors for future decision regret.

Methods: A total of 173 women seen in consultation for planned OC were followed prospectively. Surveys were administered at (1) baseline (< 1 week after initial consultation) and (2) follow-up, 6 months after planned OC among participants who froze eggs or 6 months following consultation in the absence of further communication to pursue treatment.

Endophenotypic correlates of cognitive function in reproductive-age individuals with polycystic ovary syndrome.

Objective: To characterize cognitive performance in relation to hormonal and metabolic factors in women with polycystic ovary syndrome (PCOS).

Design: Cross-sectional study.

Setting: Tertiary university center.

Learning from Online Video Education (LOVE) improves confidence in fertility treatments: a randomized controlled trial.

Fertility treatments like in vitro fertilization (IVF) or oocyte cryopreservation (OC) require the daily use of injectable gonadotropins and has been associated with treatment burden and attrition from fertility treatment. We conducted a randomized clinical trial to determine (1) whether educational videos about fertility medications improved infertility self-efficacy scale (ISES), fertility quality of life treatment (FertiQoL-T), and Perceived stress scale (PSS) scores and (2) if such videos improved confidence and reduced medication errors during a first ovarian stimulation cycle. Participants were given access to an online portal with randomized access to either placebo control videos focused on an orientation to IVF or experimental videos that reviewed the preparation and administration of medications used during ovarian stimulation in addition to the placebo videos.

Alpha Test of the Donor Conception Tool to Empower Parental Telling and Talking.

Objective: To conduct an alpha test of the prototype of a digital decision aid to help parents disclose donor conception to their children, the Donor Conception Tool to Empower Parental Telling and Talking (TELL Tool).

Design: Convergent mixed-methods design.

Setting: Virtual interviews in places convenient to the participants.

Effect of acupuncture on IVF-related anxiety: a systematic review and meta-analysis.

Patients undergoing IVF experience high levels of IVF-related state anxiety. Non-pharmacological interventions such as acupuncture may provide support, but its effect on IVF-related anxiety is unclear. This was a systematic review and meta-analysis to examine the effect of acupuncture on IVF-related state anxiety.

Decision regret after failed autologous in vitro fertilization in women ≥42 years of age.

Objective: To quantify the level of decision regret in women ≥42 years of age after autologous in vitro fertilization (IVF) and identify factors associated with moderate-to-severe regret.

Design: Cross-sectional survey.

Setting: Academic center.

Parents' experiences telling children conceived by gamete and embryo donation about their genetic origins.

Objective: To gain an in-depth understanding of parents' experiences telling children conceived by gamete and embryo donation about their genetic origins.

Design: Qualitative, descriptive.

Setting: Families' homes.

Style of meal service and feeding practices among Mexican American fathers and mothers: An analysis of video-recorded children's evening mealtime at home.

The aim of this study was to examine video-recorded observations of evening family mealtime at home among Mexican American children to help elucidate style of meal service, fathers' and mothers' feeding practices and child's eating behavior. Consistent with guidelines for coding behaviors, we analyzed observational data of evening mealtimes of 71 Mexican American children aged eight to 10 years. Regarding style of meal service, in almost all cases (96%), parents plated the child's food, with more available on the table or counter in 40% of the observations.

Association of obstructive sleep apnea risk with depression and anxiety symptoms in women with polycystic ovary syndrome.

Study Objective: To determine whether obstructive sleep apnea (OSA) risk is associated with depression and anxiety symptoms in women with polycystic ovary syndrome (PCOS).

Methods: This is a cross-sectional study of women with PCOS, by the Rotterdam criteria, seen at a single academic center between June 2017 and June 2020. Depression symptoms, anxiety symptoms, and OSA risk were assessed with the self-administered Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Berlin questionnaires, respectively.

Differences in perceived stress during ovarian stimulation between women with infertility and those pursing oocyte cryopreservation.

Objective: To determine whether the purpose of ovarian stimulation (oocyte cryopreservation [OC] versus in vitro fertilization (IVF) is associated with perceived stress before or after ovarian stimulation; and whether perceived stress is associated with ovarian stimulation outcomes.

Design: Prospective cohort study.

Setting: Academic practice.

Obesity and depression are risk factors for future eating disorder-related attitudes and behaviors in women with polycystic ovary syndrome.

Objective(s): To identify clinical predictors of future eating disorder symptoms in women with polycystic ovary syndrome (PCOS).

Design: Prospective cohort study.

Setting: University center.

New realities for the practice of egg donation: a family-building perspective.

The practice of egg donation in the United States has been based on assumptions about secrecy, anonymity, and contact among the parties that require reexamination. This article argues for the need to acknowledge that secrecy and anonymity are no longer viable assumptions and that all parties may have a strong interest in contact and connection. A shift in the narrative for the practice of egg donation from a purely medical perspective to a broader family-building perspective is described.

Clinical course of depression symptoms and predictors of enduring depression risk in women with polycystic ovary syndrome: Results of a longitudinal study.

Objective: To [1] characterize depression symptoms over time and [2] test the hypothesis that adverse metabolic parameters would associate with risk of enduring depression risk in women with polycystic ovary syndrome (PCOS).

Design: Prospective cohort study.

Setting: University center.

Sleep duration in Mexican American children: Do mothers' and fathers' parenting and family practices play a role?

This study examined parenting styles, parenting practices and family practices that may be associated with weeknight sleep duration among 8- to 10-year-old Mexican American (MA) children. This cross-sectional study of MA children used baseline data from a 2-year cohort study of mother-child pairs (n = 308) with additional data on fathers (n = 166). Children's weeknight sleep duration was accelerometer estimated and averaged for 2 weeknights.

Association among depression, symptom experience, and quality of life in polycystic ovary syndrome.

Background: Clinical stigmata of polycystic ovary syndrome include hirsutism, obesity, menstrual disturbances, and infertility. These symptoms impair health-related quality of life. Depression is also common.

Insulin resistance is associated with depression risk in polycystic ovary syndrome.

Objective: To test the hypothesis that insulin resistance is associated with depression risk in polycystic ovary syndrome (PCOS).

Design: Secondary analysis of data from a multicenter randomized trial.

Setting: Multicenter university-based clinical practices.

To freeze or not to freeze: decision regret and satisfaction following elective oocyte cryopreservation.

Objective: To characterize the degree of decision regret following elective oocyte cryopreservation (EOC) for social indications, and identify factors associated with regret.

Design: Retrospective cohort survey study.

Setting: Academic center.

Stress and coping in couples facing infertility.

Infertility presents an ideal setting for examining how stress impacts couple relationships. The effect of facing fertility problems on couple relationships is highly varied. Traditional stress and coping models are limited, because they do not account for partner interdependence.

Fathers' feeding practices and children's weight status in Mexican American families.

Mothers' feeding practices are associated with their children's weight status, but little is known about the associations between fathers' feeding practices and children's weight status. Moreover, there is a dearth of research on Latino fathers' feeding practices and children's weight status, even though Latino children suffer some of the highest obesity rates in the U.S.

Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study.

Background: Polycystic ovary syndrome (PCOS) is a very common disorder well known to be associated with insulin resistance and metabolic disease. Insulin resistance is likely involved in the promotion of the PCOS reproductive phenotype and may mediate some of the ovarian morphology seen in the disorder. The phenotype of each individual woman with PCOS can vary widely as can her metabolic risk.