Publications by authors named "Laurent Vabre"

Purpose: To evaluate the changes in visual acuity and visual perception generated by correcting higher order aberrations in highly aberrated eyes using a large-stroke adaptive optics visual simulator.

Methods: A crx1 Adaptive Optics Visual Simulator (Imagine Eyes) was used to correct and modify the wavefront aberrations in 12 keratoconic eyes and 8 symptomatic postoperative refractive surgery (LASIK) eyes. After measuring ocular aberrations, the device was programmed to compensate for the eye's wavefront error from the second order to the fifth order (6-mm pupil).

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Purpose: To evaluate the impact of higher-order aberrations on depth of focus using an adaptive optics visual simulator.

Setting: Refractive Surgery Department, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Methods: An adaptive optics simulator was used to optically introduce individual aberrations in eyes of subjects with a 6.

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Purpose: This study measured the changes in visual acuity induced by individual Zernike ocular aberrations of various root-mean-square (RMS) magnitudes.

Methods: A crx1 Adaptive Optics Visual Simulator (Imagine Eyes) was used to modify the wavefront aberrations in nine eyes. After measuring ocular aberrations, the device was programmed to compensate for the eye's wavefront error up to the 4th order and successively apply different individual Zernike aberrations using a 5-mm pupil.

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A novel deformable mirror using 52 independent magnetic actuators (MIRAO 52, Imagine Eyes) is presented and characterized for ophthalmic applications. The capabilities of the device to reproduce different surfaces, in particular Zernike polynomials up to the fifth order, are investigated in detail. The study of the influence functions of the deformable mirror reveals a significant linear response with the applied voltage.

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We have developed a white-light interference microscope for ultrahigh-resolution full-field optical coherence tomography of biological media. The experimental setup is based on a Linnik-type interferometer illuminated by a tungsten halogen lamp. En face tomographic images are calculated by a combination of interferometric images recorded by a high-speed CCD camera.

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We describe an original microscope for high-resolution optical coherence tomography applications. Our system is based on a Linnik interference microscope with high-numerical-aperture objectives. Lock-in detection of the interference signal is achieved in parallel on a CCD by use of a photoelastic birefringence modulator and full-field stroboscopic illumination with an infrared LED.

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