Interactive Visualization and On-Demand Processing of Large Volume Data: A Fully GPU-Based Out-of-Core Approach.

In a wide range of scientific fields, 3D datasets production capabilities have widely evolved in recent years, especially with the rapid increase in their sizes. As a result, many large-scale applications, including visualization or processing, have become challenging to address. A solution to this issue lies in providing out-of-core algorithms specifically designed to handle datasets significantly larger than memory.

Nucleolar sub-compartments in motion during rRNA synthesis inhibition: Contraction of nucleolar condensed chromatin and gathering of fibrillar centers are concomitant.

The nucleolus produces the large polycistronic transcript (47S precursor) containing the 18S, 5.8S and 28S rRNA sequences and hosts most of the nuclear steps of pre-rRNA processing. Among numerous components it contains condensed chromatin and active rRNA genes which adopt a more accessible conformation.