Six-year outcomes in neovascular age-related macular degeneration with ranibizumab.

Aim: To evaluate the outcomes of ≥6y ranibizumab therapy in neovascular age-related macular degeneration (AMD).

Methods: HELIX was a retrospective, observational effectiveness study using medical records of patients treated in three clinics in Belgium. Patients had neovascular AMD and were initially treated with intravitreal ranibizumab (0.

Visual acuity and factors influencing automobile driving status in 1,000 patients age 60 and older.

Background: The objective of this prospective observational study was to evaluate the number of people driving in accordance with common legal standards, measured through far binocular visual acuity, and to identify variables associated with driving habits outside of legal standards.

Methods: Subjects aged 60 years and older were recruited at a tertiary referral center (University Hospital of Mont-Godinne, Yvoir, Belgium). Ophthalmological examination was conducted in all subjects by an ophthalmologist.

Conjunctival nevi clinical features and therapeutic outcomes.

Objective: To determine the epidemiology and the clinical and therapeutic outcomes of conjunctival nevi and to identify the clinical variables statistically associated with operative excision.

Design: Prospective, observational, noncomparative case series.

Participants: Two hundred fifty-five patients with the clinical diagnosis of conjunctival nevus.

Choroidal metastasis from carcinoma of the bladder.

Purpose: To report choroidal metastasis from the newly described nested variant of urothelial carcinoma of the bladder as the initial presentation of metastatic disease.

Methods: A 58-year-old man with a history of urothelial bladder carcinoma developed progressive decreased visual acuity in the right eye. Fundus examination showed an amelanotic choroidal tumor simulating a choroidal melanoma.

Primary orbital melanoma treated with iodine-125 plaque radiotherapy.

Purpose: To report a case of primary orbital melanoma successfully managed by custom-designed iodine-125 plaque.

Design: Case report.

Methods: A 59-year-old man with no systemic or secondary melanocytic tumor was diagnosed with primary orbital melanoma after transconjunctival incisional biopsy.

Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis.

Purpose: To report the clinical and optical coherence tomography features of spherical deposits associated with recurrent toxoplasmic chorioretinitis.

Methods: Case report.

Results: Atypical, 100 microm to 150 microm, greyish deposits appeared along retinal arteries and veins as well as on the vitreoretinal interface in the macula of a 44-year-old Caucasian woman while she was being treated for recurrent toxoplasmic chorioretinitis with antiparasitic drugs and subconjunctival injection of betamethasone.

Solid cast-forming actinomycotic canaliculitis: case report.

Solid-cast forming actinomycotic canaliculitis is an uncommon cause of unilateral chronic red eye resistant to conventional topical medical therapy. The authors report the history of a 62-year old woman who was complaining of mucopurulent discharge from the right lower canaliculus for a period of 12 months. Culture yielded a few colonies of Actinomyces.