[Upper mesenteric venous thrombosis revealing familial resistance to activated protein C].

Introduction: Mesenteric venous thrombosis is a rare disease but potentially severe because of the prognosis of intestinal infarction with high mortality rate (60%).

Observation: We report the case of a 55 year-old man who presented with an upper mesenteric venous thrombosis related to a familial resistance to C reactive protein through factor V Leiden mutation.

Comments: The discovery of a mesenteric venous thrombosis requires aetiological research that is usually multifactorial.