Publications by authors named "Laurence Lambert-Cote"
Risk-stratified breast screening has been proposed as a strategy to overcome the limitations of age-based screening. A prospective cohort study was undertaken within the PERSPECTIVE I&I project, which will generate the first Canadian evidence on multifactorial breast cancer risk assessment in the population setting to inform the implementation of risk-stratified screening. Recruited females aged 40-69 unaffected by breast cancer, with a previous mammogram, underwent multifactorial breast cancer risk assessment.
View Article and Find Full Text PDFGiven the controversy over the effectiveness of age-based breast cancer (BC) screening, offering risk-stratified screening to women may be a way to improve patient outcomes with detection of earlier-stage disease. While this approach seems promising, its integration requires the buy-in of many stakeholders. In this cross-sectional study, we surveyed Canadian healthcare professionals about their views and attitudes toward a risk-stratified BC screening approach.
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- Health care professionals must actively engage in cancer prevention strategies, but this study found many lack familiarity with polygenic risk scores (PRS) and knowledge about risk-stratified breast cancer screening.
- A survey of 593 professionals showed that a significant number were unfamiliar with PRS, with 61% feeling they lacked adequate knowledge for effective BC screening.
- Most participants expressed a need for more training, preferring online courses and webinars for continuing professional development.
Article Synopsis
- The study investigates how Canadian women's understanding of genetic discrimination (GD) affects their willingness to participate in breast cancer screening programs informed by genetic risk assessments.
- It reveals that a significant portion of women (about 34.7%) are very concerned about potential misuse of their health information by employers and insurance companies, suggesting anxiety over GD.
- The findings highlight a gap in knowledge regarding legal protections against GD and emphasize the need for better public education to improve participation in genetic testing for breast cancer risk assessment.
Article Synopsis
- Risk-stratified screening for breast cancer (BC) is gaining interest in Canada but faces implementation challenges and must be acceptable to women.
- A survey conducted with 4,293 women aged 30 to 69 showed that the majority had positive attitudes towards this screening method and were comfortable sharing personal information for risk assessment.
- Most women were open to adjusting their screening frequency based on their risk level, indicating strong support for the adoption of risk-based BC screening in Canada.
Article Synopsis
- The study aimed to analyze long-term adherence patterns to adjuvant endocrine therapy (AET) in women treated for hormone-sensitive breast cancer over a 5-year period.* -
- Researchers identified five distinct groups of adherence trajectories, ranging from high adherence to rapid decline, and noted that the adherence level significantly varied based on certain factors.* -
- Findings suggest that women lacking chemotherapy or personalized care plans are more likely to experience reduced AET adherence, highlighting the importance of tailored healthcare strategies.*