Publications by authors named "Lauren Weavers"
Article Synopsis
- Development involves key interactions between the epiblast, trophectoderm, and hypoblast, which play crucial roles in forming the embryo, placenta, and yolk sac, respectively.
- Recent studies using human embryos and stem cell models have revealed how these signaling interactions occur after implantation, with specific dependencies on factors like NODAL and BMP.
- The research demonstrates both conserved and unique requirements for embryonic development in humans compared to mice, underscoring the importance of comparing different species to better understand human embryogenesis.
Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exit of ESC pluripotency. Here, we reveal that Jmjd2c facilitates this process by stabilising the assembly of mediator-cohesin complexes at lineage-specific enhancers.
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