Publications by authors named "Lauren R Hill"

Article Synopsis
  • - The study assessed how trametinib, a RAS-MAPK pathway inhibitor, affects difficult-to-treat chylous effusions in three hospitalized patients with Noonan syndrome.
  • - All patients exhibited significant improvements, including reduced lymphatic leaks and better overall health indicators such as growth, heart function, and blood health after undergoing MEK inhibition treatment.
  • - While trametinib was generally safe, causing only mild skin irritation in one patient, more extensive studies are necessary to further confirm its effectiveness and long-term safety for this group.
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 The rapid response team (RRT) is a multidisciplinary team who evaluates hospitalized patients for concerns of nonemergent clinical deterioration. RRT evaluations are mandatory for children whose Pediatric Early Warning System (PEWS) score (assessment of child's behavior, cardiovascular and respiratory status) is ≥4. We aimed to determine if there were differences in characteristics of RRT calls between children who were admitted primarily to either medical or surgical services.

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