Use of quantum dots as mass and fluorescence labels in microarray biosensing.

In this work, we demonstrate the efficacy of a Quantum Dot (QD) mass label strategy to enhance sensitivity in an interferometric technique called interferometric reflectance imaging sensor (IRIS). This biomass detection platform confers the advantage of absolute mass quantification and lower cost, easily implementable equipment. We discuss the advantages of this label when used in parallel with fluorescence detection.

Flow-through, viral co-infection assay for resource-limited settings.

Here we present a new and rapid immunofiltration assay for simultaneous detection of HIV p24 and hepatitis B virus antigens. The assay platform is composed of a 13 mm nitrocellulose filter spotted with capturing bioprobes and inserted in a Swinnex(®) syringe filter holder. Samples and reagents are flown through the nitrocellulose filter by manual pressure on the syringe.