Publications by authors named "Lauren Maier"
Objective: To examine the relationship between postpartum physical activity and maternal postnatal cardiometabolic health, breastfeeding, injury, and infant growth and development.
Design: Systematic review with random-effects meta-analysis and meta-regression.
Data Sources: Eight online databases were searched up until 12 January 2024.
Article Synopsis
- A study examined how high altitude trekking affects blood glucose levels in healthy young adults, particularly focusing on continuous glucose monitoring during a two-week trek in Nepal.
- Participants trekked 65 km from 2,860 m to 5,300 m, with glucose levels measured at various altitudes after a standardized glucose load.
- Results showed that while fasting and 24-hour glucose levels remained stable across altitudes, post-meal glucose levels varied, indicating that while glucose regulation is mostly maintained, further research is needed on postprandial glucose responses at higher altitudes.
Article Synopsis
- The study investigated how increased carbon dioxide (hypercapnia) and low oxygen levels (hypoxia) during apneas affect heart rate, specifically focusing on bradycardia (slowed heart rate).
- Researchers hypothesized that apneas with both hypercapnia and hypoxia would lead to more significant bradycardia compared to either condition alone.
- Results showed that hypoxia was the main factor causing bradycardia, with combined hypercapnia and hypoxia leading to similar heart rate responses as hypoxia alone.
The purpose of this systematic review and meta-analysis was to examine the effects of exercise training on muscle sympathetic nerve activity (MSNA) in humans. Studies included exercise interventions [randomized controlled trials (RCTs), nonrandomized controlled trials (non-RCTs), or pre-to-post intervention] that reported on adults (≥18 yr) where MSNA was directly assessed using microneurography, and relevant outcomes were assessed [MSNA (total activity, burst frequency, burst incidence, amplitude), heart rate, blood pressure (systolic blood pressure, diastolic blood pressure, or mean blood pressure), and aerobic capacity (maximal or peak oxygen consumption)]. Forty intervention studies ( = 1,253 individuals) were included.
View Article and Find Full Text PDFThe effect of hypoxemia on muscle sympathetic nerve activity and cardiovascular function: a systematic review and meta-analysis.
Am J Physiol Regul Integr Comp Physiol
November 2023
We conducted a systematic review and meta-analysis to determine the effect of acute poikilocapnic, high-altitude, and acute isocapnia hypoxemia on muscle sympathetic nerve activity (MSNA) and cardiovascular function. A comprehensive search across electronic databases was performed until June 2021. All observational designs were included: population (healthy individuals); exposures (MSNA during hypoxemia); comparators (hypoxemia severity and duration); outcomes (MSNA; heart rate, HR; and mean arterial pressure, MAP).
View Article and Find Full Text PDFBackground: We conducted meta-analyses to identify relationships between obstructive sleep apnea (OSA) severity, muscle sympathetic nerve activity (MSNA), and blood pressure (BP). We quantified the effect of OSA treatment on MSNA.
Methods: Structured searches of electronic databases were performed until June 2021.